Gene: SIK1
Official Full Name: salt inducible kinase 1provided by HGNC
Gene Summary: This gene encodes a serine/threonine protein kinase that contains a ubiquitin-associated (UBA) domain. The encoded protein is a member of the adenosine monophosphate-activated kinase (AMPK) subfamily of kinases that play a role in conserved signal transduction pathways. A mutation in this gene is associated with early infantile epileptic encephalopathy 30. [provided by RefSeq, Nov 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00024 | SIK1 Knockout cell line (EA.hy926) | Human | SIK1 | 1:2~1:3 | Negative | Online Inquiry |
SIK1 Gene Knockout Cell Lines represent a groundbreaking tool in molecular biology that allows researchers to explore the specific functions and mechanisms attributed to the SIK1 gene. These engineered cell lines have undergone targeted genetic modifications resulting in the complete ablation of SIK1 expression, which plays a crucial role in cellular processes such as metabolism, apoptosis, and inflammation. By utilizing CRISPR/Cas9 technology, our knockout cell lines enable precise studies of SIK1 function, thereby providing versatile platforms for assaying its effects on various cellular pathways and disease models.
The SIK1 gene, a member of the AMP-activated protein kinase family, is implicated in the regulation of energy homeostasis and cellular signaling, making its study vital in understanding metabolic disorders and cancer. The SIK1 Gene Knockout Cell Lines are essential in elucidating the underlying mechanisms leading to aberrant cell behavior that characterizes many diseases. Researchers can conduct detailed investigations into SIK1's role in cellular responses to stress, hormone signaling, and tumorigenesis, contributing significantly to both basic and applied research.
Compared to conventional cell lines, these knockout models provide unparalleled specificity and reliability in experiments, ensuring that observed effects are directly attributable to the loss of SIK1 function. This advantage is crucial for drug discovery, biomarker development, and therapeutic interventions targeting diseases where SIK1 plays a pivotal role.
Researchers and clinicians will find value in these cell lines for their ability to streamline experimental workflows and enhance reproducibility. Our SIK1 Gene Knockout Cell Lines are backed by rigorous quality control and validation, ensuring that customers receive high-fidelity models for their research endeavors.
With extensive experience in developing cutting-edge biological products, our company is dedicated to empowering scientific advancement through innovative solutions, solidifying our position as a trusted partner for researchers striving to unlock the complexities of gene function and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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