Gene: SHROOM1
Official Full Name: shroom family member 1provided by HGNC
Gene Summary: SHROOM family members play diverse roles in the development of the nervous system and other tissues (Hagens et al., 2006 [PubMed 16615870]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26429 | SHROOM1 Knockout cell line (HeLa) | Human | SHROOM1 | 1:3~1:6 | Negative | Online Inquiry |
KO26430 | SHROOM1 Knockout cell line (HCT 116) | Human | SHROOM1 | 1:2~1:4 | Negative | Online Inquiry |
KO26431 | SHROOM1 Knockout cell line (HEK293) | Human | SHROOM1 | 1:3~1:6 | Negative | Online Inquiry |
KO26432 | SHROOM1 Knockout cell line (A549) | Human | SHROOM1 | 1:3~1:4 | Negative | Online Inquiry |
SHROOM1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the SHROOM1 gene, a critical component in cellular signaling and morphology regulation. SHROOM1 is involved in actin dynamics, contributing significantly to processes such as cell shape determination, epithelial integrity, and neuronal function. By creating specific SHROOM1 knockout lines, researchers can dissect the gene’s role in various biological pathways and its implications in developmental biology and disease states.
These cell lines function by utilizing CRISPR-Cas9 genome editing technology to achieve precise gene deletion, enabling the study of SHROOM1’s contributions to cellular processes without interference from the native gene. The absence of SHROOM1 allows for in-depth analysis of actin cytoskeletal reorganization, which is crucial for understanding numerous cellular functions, including migration, adhesion, and morphogenetic processes. This model is particularly valuable in research pertaining to neurodevelopmental disorders and other pathologies linked to cytoskeletal dysregulation.
In scientific and clinical research settings, SHROOM1 Gene Knockout Cell Lines serve as an invaluable tool for elucidating the mechanistic roles of SHROOM1 in health and disease. They offer a unique advantage over traditional models that may harbor compensatory mechanisms, thereby providing clearer insights into gene function. Compared to existing alternatives, these cell lines provide consistency and reproducibility, essential attributes for high-impact research.
For researchers and clinicians alike, these knockout cell lines represent a powerful resource for experimental validation and drug discovery efforts aimed at disorders influenced by SHROOM1. With a strong foundation in molecular biology and genetic editing, our company specializes in providing cutting-edge biological tools that empower the scientific community, ensuring that researchers gain access to the most precise and reliable models for their investigations.
Please note that all services are for research use only. Not intended for any clinical use.
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