Gene: SHISA5
Official Full Name: shisa family member 5provided by HGNC
Gene Summary: This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. Related pseudogenes of this gene are found on chromosome X. [provided by RefSeq, Apr 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22805 | SHISA5 Knockout cell line (HeLa) | Human | SHISA5 | 1:3~1:6 | Negative | Online Inquiry |
KO22806 | SHISA5 Knockout cell line (HCT 116) | Human | SHISA5 | 1:2~1:4 | Negative | Online Inquiry |
KO22807 | SHISA5 Knockout cell line (HEK293) | Human | SHISA5 | 1:3~1:6 | Negative | Online Inquiry |
KO22808 | SHISA5 Knockout cell line (A549) | Human | SHISA5 | 1:3~1:4 | Negative | Online Inquiry |
SHISA5 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of SHISA5, a gene implicated in various cellular processes, including synaptic transmission and neurodevelopment. These knockout cell lines are generated through precise genome-editing techniques, such as CRISPR-Cas9, allowing for the complete ablation of the SHISA5 gene, which is essential for elucidating its biological role.
The primary function of the SHISA5 Gene Knockout Cell Lines is to create a controlled environment in which researchers can investigate the downstream effects of SHISA5 depletion. By analyzing the phenotype of these modified cells, scientists can determine the gene's involvement in pathways such as neurotransmitter signaling and cellular response to stimuli. Furthermore, these knockout models provide an invaluable platform for drug discovery, as they enable the assessment of therapeutic compounds aimed at modulating SHISA5-related pathways.
From a scientific perspective, the significance of SHISA5 Gene Knockout Cell Lines lies in their potential applications in neurobiology and pharmacology research. Understanding SHISA5 functions may lead to breakthroughs in treating neurological disorders, thereby advancing clinical therapies. Moreover, these knockout lines facilitate comparative studies with wild-type cells, enhancing the robustness of experimental findings.
One of the unique selling points of our SHISA5 Gene Knockout Cell Lines is the precision of our genetic modifications, which minimizes off-target effects, ensuring that the results are credible. Additionally, our cell lines are thoroughly validated for stability and reproducibility, streamlining experimental protocols for researchers seeking reliable results.
For researchers and clinicians, the ability to precisely manipulate gene expression significantly enhances experimental accuracy and offers insights into complex biological systems. Our SHISA5 Gene Knockout Cell Lines not only expedite research timelines but also provide a reliable toolset for cutting-edge studies.
At [Company Name], we pride ourselves on our commitment to scientific excellence and innovation, specializing in advanced biological products that support the research community. Our expertise ensures that researchers have access to high-quality, well-characterized cell lines that empower their work and advance our understanding of critical biological processes.
Please note that all services are for research use only. Not intended for any clinical use.
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