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SGTA Knockout Cell Lines

Gene: SGTA

Official Full Name: small glutamine rich tetratricopeptide repeat co-chaperone alphaprovided by HGNC

Gene Summary: This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05911 SGTA Knockout cell line (HeLa) Human SGTA 1:3~1:6 Negative Online Inquiry
KO05912 SGTA Knockout cell line (HCT 116) Human SGTA 1:2~1:4 Negative Online Inquiry
KO05913 SGTA Knockout cell line (HEK293) Human SGTA 1:3~1:6 Negative Online Inquiry
KO05914 SGTA Knockout cell line (A549) Human SGTA 1:3~1:4 Negative Online Inquiry

Background

SGTA Gene Knockout Cell Lines are specially engineered cellular models designed to effectively eliminate the expression of the SGTA gene, allowing researchers to explore its role in various biological processes and disease states. These knockout cell lines serve as a powerful tool for elucidating gene function by creating a controlled environment where the effects of SGTA deficiency can be studied in detail.

The key function of SGTA Gene Knockout Cell Lines lies in their ability to facilitate the investigation of the SGTA gene's involvement in processes such as protein quality control, cellular stress responses, and viral interactions. By utilizing CRISPR-Cas9 technology for precise genome editing, these cell lines provide researchers with a robust mechanism to generate loss-of-function mutants. Consequently, they can assess the resultant phenotypic variations and the molecular pathways influenced by SGTA, accelerating discoveries in the fields of cellular biology and translational medicine.

Scientifically, SGTA Gene Knockout Cell Lines hold significant importance for both research and clinical applications. They are instrumental in drug discovery efforts aimed at targeting SGTA-related pathways and in studying conditions such as cancer and neurodegenerative diseases, where SGTA has been implicated. These cell lines enable researchers to develop potential therapeutic interventions or diagnostic markers.

Compared to alternative cellular models, SGTA Gene Knockout Cell Lines offer several distinct advantages. Their precise gene knockout capability yields a more accurate portrayal of SGTA-related effects than traditional overexpression methods or less-targeted siRNA approaches. Additionally, these cell lines can be readily integrated into various experimental platforms, allowing for high-throughput screening, functional assays, and other investigative methodologies.

For researchers and clinicians, the value of SGTA Gene Knockout Cell Lines lies in their contribution to a deeper understanding of complex biological systems and the potential to drive innovation in clinical applications. This product empowers users to make significant strides towards unraveling the intricacies of gene function and its implications in health and disease.

Our company is committed to advancing scientific research through the provision of high-quality, accurately engineered biological products such as SGTA Gene Knockout Cell Lines, equipped to support breakthroughs in understanding gene function and potential therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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