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SETD6 Knockout Cell Lines

Gene: SETD6

Official Full Name: SET domain containing 6, protein lysine methyltransferaseprovided by HGNC

Gene Summary: This gene encodes a methyltransferase that adds a methyl group to the histone H2AZ, which is involved in nuclear receptor-dependent transcription. The protein also interacts with several endogenous proteins which are involved in nuclear hormone receptor signaling. A related pseudogene is located on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14187 SETD6 Knockout cell line (HeLa) Human SETD6 1:3~1:6 Negative Online Inquiry
KO14188 SETD6 Knockout cell line (HCT 116) Human SETD6 1:2~1:4 Negative Online Inquiry
KO14189 SETD6 Knockout cell line (HEK293) Human SETD6 1:3~1:6 Negative Online Inquiry
KO14190 SETD6 Knockout cell line (A549) Human SETD6 1:3~1:4 Negative Online Inquiry

Background

SETD6 Gene Knockout Cell Lines are a specialized biological product designed for advanced research applications, specifically focusing on the investigation of the SETD6 gene, which encodes a lysine methyltransferase involved in various cellular processes, including gene regulation and chromatin remodeling. These cell lines have been engineered to disrupt the expression of the SETD6 gene, enabling researchers to study the functional consequences of its absence in various biological contexts.

The primary mechanism of these cell lines operates through CRISPR/Cas9-mediated gene editing, which allows for precise genetic modifications. By knocking out the SETD6 gene, researchers can observe changes in cellular behavior, gene expression profiles, and signaling pathways. This is particularly important for dissecting the role of SETD6 in diseases such as cancer and neurological disorders, where aberrations in gene expression and epigenetic regulation can lead to pathogenesis.

The scientific significance of SETD6 Gene Knockout Cell Lines lies in their versatility in both research and clinical settings. These models empower scientists to elucidate the molecular mechanisms underlying cellular processes and disease mechanisms, paving the way for potential therapeutic interventions. Given the increasing interest in epigenetics and gene regulation, these cell lines serve as invaluable tools in drug discovery and biomarker development.

Compared to conventional knockout models, SETD6 Gene Knockout Cell Lines offer superior specificity and efficiency, resulting in more reliable experimental outcomes. Moreover, these cell lines are designed for high reproducibility, ensuring consistent data across studies.

For researchers and clinicians aiming to explore the intricacies of gene function and regulation, SETD6 Gene Knockout Cell Lines represent a significant advancement in biological research tools. They enable groundbreaking discoveries that can lead to novel therapeutic approaches. Our company is committed to providing high-quality biological products backed by extensive expertise in gene editing and cell line development, ensuring our customers have access to cutting-edge research tools that drive innovation in the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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