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SETD3 Knockout Cell Lines

Gene: SETD3

Official Full Name: SET domain containing 3, actin N3(tau)-histidine methyltransferaseprovided by HGNC

Gene Summary: Enables protein-L-histidine N-tele-methyltransferase activity. Involved in actin modification and peptidyl-histidine methylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25104 SETD3 Knockout cell line (HeLa) Human SETD3 1:3~1:6 Negative Online Inquiry
KO25105 SETD3 Knockout cell line (HCT 116) Human SETD3 1:2~1:4 Negative Online Inquiry
KO25106 SETD3 Knockout cell line (HEK293) Human SETD3 1:3~1:6 Negative Online Inquiry
KO25107 SETD3 Knockout cell line (A549) Human SETD3 1:3~1:4 Negative Online Inquiry

Background

SETD3 Gene Knockout Cell Lines are advanced cellular models designed for the genetic study of the SETD3 gene, known for its role in regulating various biological processes, including cellular signaling pathways and gene expression. These knockout cell lines are engineered to have a targeted disruption of the SETD3 gene, allowing researchers to investigate the gene's functional implications in both physiological and pathological contexts.

The core mechanism of these cell lines involves the use of CRISPR-Cas9 gene editing technology, which enables precise alterations within the genome. By knocking out the SETD3 gene, researchers can observe the resultant phenotypic changes, elucidate molecular mechanisms of disease progression, and understand interactions within the cellular environment. This can be invaluable in studies focusing on cancer biology, neurodegenerative diseases, and metabolic disorders, where SETD3 is implicated.

The scientific significance of SETD3 Gene Knockout Cell Lines is underscored by their application in both basic research and clinical settings. They provide a platform for the identification of novel biomarkers and therapeutic targets, thereby facilitating drug discovery and development efforts. Additionally, these models can enhance translatable insights into gene function and regulation, driving forward the field of gene therapy.

Compared to alternative cell lines, the unique advantage of our SETD3 knockout lines lies in their tailored design, which guarantees fidelity in gene disruption and reproducibility across experiments. This increases the accuracy of experimental results, allowing researchers to generate more reliable data. Furthermore, our product comes with extensive support materials, including experimental protocols and characterization data, to streamline the integration into existing research workflows.

For researchers and clinicians seeking to investigate the roles of the SETD3 gene in biological systems, these knockout cell lines represent a valuable tool for advancing their studies. As a leader in biological product development with a commitment to scientific excellence, we provide these robust models backed by rigorous quality control and extensive expertise in genetic engineering, ensuring that you receive a product that meets the highest standards of reliability and performance.

Please note that all services are for research use only. Not intended for any clinical use.

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