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SERTAD2 Knockout Cell Lines

Gene: SERTAD2

Official Full Name: SERTA domain containing 2provided by HGNC

Gene Summary: Predicted to enable transcription coactivator activity. Acts upstream of or within negative regulation of cell growth. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32755 SERTAD2 Knockout cell line (HeLa) Human SERTAD2 1:3~1:6 Negative Online Inquiry
KO32756 SERTAD2 Knockout cell line (HCT 116) Human SERTAD2 1:2~1:4 Negative Online Inquiry
KO32757 SERTAD2 Knockout cell line (HEK293) Human SERTAD2 1:3~1:6 Negative Online Inquiry
KO32758 SERTAD2 Knockout cell line (A549) Human SERTAD2 1:3~1:4 Negative Online Inquiry

Background

SERTAD2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the SERTAD2 gene, which is implicated in various cellular processes, including cell cycle regulation and apoptosis. These knockout cell lines serve as crucial tools for scientists aiming to delineate the biological roles of SERTAD2 in cellular functions and disease mechanisms. By eliminating the expression of SERTAD2, researchers can investigate its contribution to pathways such as oncogenesis, differentiation, and neuronal signaling, offering valuable insights into the molecular underpinnings of diseases like cancer and neurodegenerative disorders.

The primary mechanism by which SERTAD2 Gene Knockout Cell Lines function is through the disruption of SERTAD2 protein synthesis, which affects downstream signaling pathways related to cell survival and proliferation. This creates an environment that allows for the in-depth study of compensatory mechanisms activated in response to the absence of SERTAD2. Such investigations are vital for understanding how cells adapt to genetic disruptions, paving the way for potential therapeutic targets.

In the research and clinical settings, these cell lines hold significant scientific importance. They can be employed for drug screening, functional genomics, and investigating gene-targeting therapies. By providing a standardized model system, SERTAD2 Gene Knockout Cell Lines facilitate reproducibility and comparability across studies, which is critical for validating experimental outcomes.

Compared to alternative models, such as SERTAD2 knockdown or overexpression systems, our knockout cell lines provide a complete absence of the target gene, allowing for clearer conclusions about the gene's roles without the confounding effects of residual protein expression. This rigor enhances the fidelity of experimental designs, making the SERTAD2 Gene Knockout Cell Lines an invaluable resource in the toolkit of modern molecular biology.

Ultimately, the value of SERTAD2 Gene Knockout Cell Lines lies in their ability to support cutting-edge research while delivering insights that may lead to novel therapeutic strategies. Our commitment to excellence in genetic engineering ensures that these cell lines are produced with the highest quality controls, supported by our expertise in molecular biology and a robust history of providing innovative solutions for the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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