Gene: SEPTIN9
Official Full Name: septin 9provided by HGNC
Gene Summary: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31504 | SEPTIN9 Knockout cell line (HeLa) | Human | SEPTIN9 | 1:3~1:6 | Negative | Online Inquiry |
KO31505 | SEPTIN9 Knockout cell line (HCT 116) | Human | SEPTIN9 | 1:2~1:4 | Negative | Online Inquiry |
KO31506 | SEPTIN9 Knockout cell line (HEK293) | Human | SEPTIN9 | 1:3~1:6 | Negative | Online Inquiry |
KO31507 | SEPTIN9 Knockout cell line (A549) | Human | SEPTIN9 | 1:3~1:4 | Negative | Online Inquiry |
SEPTIN9 Gene Knockout Cell Lines are a cutting-edge biological research tool designed to facilitate the elucidation of gene function and regulation, specifically targeting the SEPTIN9 gene, which encodes for a key protein involved in various cellular processes, including cytokinesis and cellular scaffolding. These cell lines enable researchers to investigate the implications of SEPTIN9 deficiencies in a controlled cellular environment, effectively allowing for a detailed exploration of its role in health and disease.
The key function of these knockout cell lines lies in their ability to eliminate the expression of the SEPTIN9 gene, thereby enabling the study of gene-specific pathways without the confounding effects of the protein. This mechanism distinguishes them as premier models for researchers examining cellular dynamics, oncogenesis, and neurodegenerative diseases where SEPTIN9 has been implicated. By analyzing the phenotypic changes and associated molecular pathways of these cells, scientists can gain insights into the biological processes governed by SEPTIN9, potentially identifying new therapeutic targets.
The scientific importance of SEPTIN9 Gene Knockout Cell Lines extends to both basic research and clinical applications. In research settings, these models are invaluable for generating hypotheses and testing the effects of gene disruption on cell behavior. Clinically, understanding SEPTIN9's role can provide insights into its involvement in diseases such as cancer, where its dysregulation could be a contributing factor.
What sets SEPTIN9 Gene Knockout Cell Lines apart from traditional models is their specificity and ease of use. Unlike other knockout systems that may introduce off-target effects, these cell lines are developed to ensure a precise genetic alteration, providing researchers with reliable and reproducible results. The convenience of having a ready-to-use model accelerates the timelines for experiments and enhances the efficiency of research projects.
In summary, SEPTIN9 Gene Knockout Cell Lines represent a valuable asset for researchers and clinicians interested in innovative gene studies and their implications in disease mechanisms. Our company, with a strong focus on developing high-quality biological research tools, is committed to enabling groundbreaking discoveries and advancing the field of genetics.
Please note that all services are for research use only. Not intended for any clinical use.
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