Gene: SEPTIN2
Official Full Name: septin 2provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in several processes, including cilium assembly; regulation of exocytosis; and smoothened signaling pathway. Predicted to act upstream of or within regulation of L-glutamate import across plasma membrane and regulation of protein localization. Located in several cellular components, including cytoskeleton; photoreceptor connecting cilium; and sperm annulus. Part of septin complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36394 | SEPTIN2 Knockout cell line (HeLa) | Human | SEPTIN2 | 1:3~1:6 | Negative | Online Inquiry |
KO36395 | SEPTIN2 Knockout cell line (HCT 116) | Human | SEPTIN2 | 1:2~1:4 | Negative | Online Inquiry |
KO36396 | SEPTIN2 Knockout cell line (HEK293) | Human | SEPTIN2 | 1:3~1:6 | Negative | Online Inquiry |
KO36397 | SEPTIN2 Knockout cell line (A549) | Human | SEPTIN2 | 1:3~1:4 | Negative | Online Inquiry |
SEPTIN2 Gene Knockout Cell Lines are a specialized collection of cell lines that have been genetically engineered to contain a complete knockout of the SEPTIN2 gene. SEPTIN2 is a member of the septin protein family, which plays a crucial role in various cellular processes, including cell division, cytoskeletal organization, and membrane dynamics. By disrupting the expression of SEPTIN2, these knockout cell lines serve as powerful tools for investigating the gene's function and its contributions to critical cellular pathways.
These cell lines provide researchers with the ability to study the biological effects of SEPTIN2 loss, offering insights into its role in disease mechanisms, particularly in cancer progression and neurodegenerative disorders. The mechanisms of action involve the analysis of cellular morphology, proliferation rates, and apoptotic pathways, allowing for comprehensive assessments of how SEPTIN2 influences cellular behavior and signaling cascades.
The scientific importance of SEPTIN2 Gene Knockout Cell Lines is underscored by their application in various research settings, including drug discovery, functional genomics, and therapeutic development. Researchers can leverage these models to elucidate the pathways involved in cell cycle regulation and investigate potential therapeutic targets for diseases linked to septin dysfunction.
What sets these cell lines apart from other genetic models is their rigorously validated knockout efficiency and the robust background they offer for comparative studies. Furthermore, the versatility of these cell lines allows for straightforward integration into existing experimentation workflows, enhancing researchers’ ability to assess the effects of gene modulation in a reliable context.
For clinicians and researchers alike, SEPTIN2 Gene Knockout Cell Lines provide invaluable resources that can accelerate the interpretation of SEPTIN2's role in diseases, leading to impactful findings that could inform clinical applications. Our company prides itself on its expertise in genetic engineering and its commitment to providing high-quality biological products that meet the rigorous demands of modern research.
Please note that all services are for research use only. Not intended for any clinical use.
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