Gene: SEC22C
Official Full Name: SEC22 homolog C, vesicle trafficking proteinprovided by HGNC
Gene Summary: This gene encodes a member of the SEC22 family of vesicle trafficking proteins. The encoded protein is localized to the endoplasmic reticulum and may play a role in the early stages of ER-Golgi protein trafficking. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33569 | SEC22C Knockout cell line (HeLa) | Human | SEC22C | 1:3~1:6 | Negative | Online Inquiry |
KO33570 | SEC22C Knockout cell line (HCT 116) | Human | SEC22C | 1:2~1:4 | Negative | Online Inquiry |
KO33571 | SEC22C Knockout cell line (HEK293) | Human | SEC22C | 1:3~1:6 | Negative | Online Inquiry |
KO33572 | SEC22C Knockout cell line (A549) | Human | SEC22C | 1:3~1:4 | Negative | Online Inquiry |
SEC22C Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the SEC22C gene, a key player in the regulation of intracellular vesicle transport and exocytosis. This product serves as a vital tool for scientists and researchers aiming to elucidate the role of the SEC22C protein in cellular processes, including membrane trafficking and secretion dynamics. By employing targeted CRISPR/Cas9 technology, these knockout cell lines provide a validated model to investigate the functional consequences of SEC22C depletion.
The foremost function of the SEC22C Gene Knockout Cell Lines lies in their ability to facilitate studies on vesicular transport mechanisms. SEC22C is implicated in the transport of proteins from the endoplasmic reticulum to the Golgi apparatus; thus, these knockout lines enable researchers to dissect pathways involved in protein secretion and to assess the downstream effects of altered vesicle dynamics. As a result, studies utilizing these cell lines can provide valuable insights into various diseases where vesicle transport is disrupted, including neurodegenerative disorders and metabolic syndromes.
In terms of scientific significance, SEC22C Gene Knockout Cell Lines have essential applications in both basic research and clinical conditions. They permit researchers to map cellular signaling pathways and identify potential therapeutic targets related to exocytosis-related diseases. Furthermore, these cell lines represent robust platforms for high-throughput screening and drug discovery efforts focused on modulating exocytotic processes.
One of the unique selling points of the SEC22C Gene Knockout Cell Lines is the precision with which they were generated. Unlike traditional knockdown models, which may retain residual gene function, these knockout cell lines provide a complete loss-of-function scenario, ensuring the elimination of confounding variables in experimental designs. Additionally, they are compatible with various assay systems, making them a versatile option for diverse applications.
Researchers and clinicians will find value in utilizing SEC22C Gene Knockout Cell Lines for their superior reliability and reproducibility, which are crucial for achieving publishable results. By choosing this product, users gain access to a comprehensive resource for understanding complex extracellular processes, ultimately paving the way for innovative therapeutic strategies.
Our company prides itself on delivering high-quality biological products backed by extensive expertise in genetic engineering and molecular biology. With a commitment to advancing research, we provide reliable tools that empower scientists in their pursuit of groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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