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SDCCAG8 Knockout Cell Lines

Gene: SDCCAG8

Official Full Name: SHH signaling and ciliogenesis regulator SDCCAG8provided by HGNC

Gene Summary: This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31496 SDCCAG8 Knockout cell line (HeLa) Human SDCCAG8 1:3~1:6 Negative Online Inquiry
KO31497 SDCCAG8 Knockout cell line (HCT 116) Human SDCCAG8 1:2~1:4 Negative Online Inquiry
KO31498 SDCCAG8 Knockout cell line (HEK293) Human SDCCAG8 1:3~1:6 Negative Online Inquiry
KO31499 SDCCAG8 Knockout cell line (A549) Human SDCCAG8 1:3~1:4 Negative Online Inquiry

Background

SDCCAG8 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the function of the SDCCAG8 gene, which has been implicated in various cellular processes, including ciliogenesis and cellular signaling pathways. By utilizing CRISPR/Cas9 genome-editing technology, these cell lines have been effectively rendered deficient in the SDCCAG8 gene, enabling researchers to gain insights into the gene's role in disease mechanisms and cellular physiology.

The primary function of the SDCCAG8 Gene Knockout Cell Lines lies in their ability to mimic pathological conditions by providing a platform for evaluating the effects of SDCCAG8 deficiency. The absence of this gene disrupts key cellular functions, making these cell lines valuable for studying developmental biology, genetics, and even cancer research. The mechanisms by which these cell lines operate include alterations in cellular morphology, signaling cascades, and interactions with neighboring cells, providing a multifaceted understanding of the gene's biological significance.

Scientific research utilizing these cells is critical for elucidating the molecular pathways associated with SDCCAG8, which can lead to potential therapeutic targets for diseases linked to ciliary dysfunction and related disorders. Unlike traditional cell lines that may only partially represent the effects of gene knockouts, our SDCCAG8 Gene Knockout Cell Lines demonstrate precise genetic alterations, ensuring reliable and reproducible results.

A significant advantage of our product is its ease of use alongside a wide compatibility with existing laboratory protocols, saving valuable time for researchers. Moreover, these cell lines are rigorously validated and quality-controlled, ensuring that they meet high scientific standards compared to competitor products, which may present variability in genotype and phenotype.

Researchers and clinicians looking to deepen their understanding of SDCCAG8 and related pathways will find immense value in the availability of these specialized knockout cell lines. They enable not only the exploration of fundamental genetic principles but also the assessment of novel therapeutic strategies. Our company's expertise in genetic engineering and commitment to advancing biological knowledge ensures that these cell lines are a reliable resource in the pursuit of scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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