Gene: SCYL2
Official Full Name: SCY1 like pseudokinase 2provided by HGNC
Gene Summary: The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06923 | SCYL2 Knockout cell line (HeLa) | Human | SCYL2 | 1:3~1:6 | Negative | Online Inquiry |
KO06924 | SCYL2 Knockout cell line (HCT 116) | Human | SCYL2 | 1:2~1:4 | Negative | Online Inquiry |
KO06925 | SCYL2 Knockout cell line (HEK293) | Human | SCYL2 | 1:3~1:6 | Negative | Online Inquiry |
KO06926 | SCYL2 Knockout cell line (A549) | Human | SCYL2 | 1:3~1:4 | Negative | Online Inquiry |
SCYL2 Gene Knockout Cell Lines are an innovative tool used in molecular biology to study the function of the SCYL2 gene and its role in cellular processes. These genetically modified cell lines are specifically designed to have the SCYL2 gene disrupted, allowing researchers to investigate the effects of its absence in various biological contexts. This product facilitates the exploration of SCYL2’s involvement in critical processes such as intracellular transport, signal transduction, and potentially disease mechanisms.
The key function of SCYL2 Gene Knockout Cell Lines lies in their ability to mimic genetic conditions associated with SCYL2 deletions. Researchers can utilize these cell lines to assess changes in cellular behavior, protein interaction networks, and overall phenotypic alterations. By employing advanced techniques such as CRISPR-Cas9 technology to create precise deletions in the SCYL2 gene, these cell lines provide an invaluable resource for understanding gene function and developing therapeutic strategies.
The scientific importance of these cell lines extends across various fields, including cancer research, neurobiology, and drug development. They enable a deeper understanding of how SCYL2 contributes to diseases at the cellular level and can be instrumental in validating potential drug targets.
Compared to traditional methods of gene disruption, such as random mutagenesis or RNA interference, SCYL2 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility. Researchers can achieve consistent results and reduced variability, making them an efficient choice for studies that require rigorous genetic manipulation.
For researchers and clinicians focusing on genetic research, disease modeling, or drug testing, SCYL2 Gene Knockout Cell Lines provide a crucial resource. They not only enhance the understanding of SCYL2’s biological role but also pave the way for novel therapeutic approaches targeting related pathways.
With expertise in developing cutting-edge biological products, our company is committed to advancing research and discovery through innovative solutions like the SCYL2 Gene Knockout Cell Lines, ensuring that researchers have the tools they need to drive scientific progress.
Please note that all services are for research use only. Not intended for any clinical use.
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