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SCOC Knockout Cell Lines

Gene: SCOC

Official Full Name: short coiled-coil proteinprovided by HGNC

Gene Summary: This gene encodes a short coiled-coiled domain-containing protein that localizes to the Golgi apparatus. The encoded protein interacts with ADP-ribosylation factor-like proteins. Pseudogenes of this gene are found on chromosomes 1 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14309 SCOC Knockout cell line (HeLa) Human SCOC 1:3~1:6 Negative Online Inquiry
KO14310 SCOC Knockout cell line (HCT 116) Human SCOC 1:2~1:4 Negative Online Inquiry
KO14311 SCOC Knockout cell line (HEK293) Human SCOC 1:3~1:6 Negative Online Inquiry
KO14312 SCOC Knockout cell line (A549) Human SCOC 1:3~1:4 Negative Online Inquiry

Background

SCOC Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study and functional characterization of the Stem Cell Oligodendrocyte Cell (SCOC) gene. Utilizing advanced CRISPR-Cas9 genome editing techniques, these cell lines enable researchers to achieve precise deletions of the SCOC gene, thereby creating a platform for the investigation of its biological roles and implications in various cellular processes.

The primary functionality of the SCOC Gene Knockout Cell Lines lies in their ability to elucidate the effects of the absence of the SCOC gene on cellular behavior and differentiation pathways. By comparing the knockout lines to their wild-type counterparts, scientists can assess changes in signaling pathways, morphology, gene expression profiles, and overall cell function. This capability is vital for understanding the role of SCOC in neurodevelopment, myelination, and potentially in neurodegenerative diseases.

The scientific importance of these cell lines extends to both basic research and clinical applications. In research settings, they serve as invaluable tools for dissecting gene function, validating targets for therapeutic interventions, and developing models for disease conditions. In clinical applications, insights garnered from these studies could lead to new strategies for the treatment of disorders related to oligodendrocyte function, such as multiple sclerosis or leukodystrophies.

When compared to alternative models, the SCOC Gene Knockout Cell Lines hold several key advantages. The use of CRISPR-Cas9 not only ensures a high efficiency of gene knockouts but also minimizes off-target effects, resulting in more reliable data. Furthermore, the ability to generate stable knockout cell lines allows for long-term studies and reproducibility of experimental results.

For researchers and clinicians focused on neurobiology, the SCOC Gene Knockout Cell Lines represent a powerful resource for advancing our understanding of oligodendrocyte biology and its implications in health and disease. Our company prides itself on providing quality, well-characterized biological products that empower the scientific community, drawing on years of expertise in cellular engineering to deliver innovative and reliable solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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