Gene: SCLT1
Official Full Name: sodium channel and clathrin linker 1provided by HGNC
Gene Summary: This gene encodes an adaptor protein. Studies of a related gene in rat suggest that the encoded protein functions to link clathrin to the sodium channel protein type 10 subunit alpha protein. The encoded protein has also been identified as a component of distal appendages of centrioles that is necessary for ciliogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26526 | SCLT1 Knockout cell line (HeLa) | Human | SCLT1 | 1:3~1:6 | Negative | Online Inquiry |
KO26527 | SCLT1 Knockout cell line (HCT 116) | Human | SCLT1 | 1:2~1:4 | Negative | Online Inquiry |
KO26528 | SCLT1 Knockout cell line (HEK293) | Human | SCLT1 | 1:3~1:6 | Negative | Online Inquiry |
KO26529 | SCLT1 Knockout cell line (A549) | Human | SCLT1 | 1:3~1:4 | Negative | Online Inquiry |
SCLT1 Gene Knockout Cell Lines are genetically engineered cell lines where the SCLT1 gene has been deliberately inactivated or "knocked out," providing a crucial tool for studying the biological roles of this gene in various cellular processes. These cell lines are invaluable for researchers seeking to understand the functional consequences of SCLT1 deletion on cell behavior, particularly in relation to development, signaling pathways, and disease models.
The primary mechanism at play in SCLT1 Gene Knockout Cell Lines involves the use of CRISPR-Cas9 technology, which allows for precise genomic editing. By creating specific mutations in the SCLT1 gene, researchers can investigate the impact of gene loss on cellular function, providing insights into its regulatory roles in physiological and pathological contexts. This capability is essential for elucidating gene function and its higher-order interactions within cellular networks, leading to a deeper understanding of various biological phenomena.
The scientific importance of these knockout cell lines extends into both research and clinical applications. In research settings, they serve as model systems for studying gene function, drug response, and disease progression. Clinically, understanding the role of SCLT1 may highlight new therapeutic targets for conditions such as cancer, metabolic syndromes, or inflammatory diseases, paving the way for the development of innovative treatment modalities.
Unlike conventional cell lines, SCLT1 Gene Knockout Cell Lines offer specific advantages, including the ability to accurately model the effects of gene loss without the confounding factors associated with incomplete knockdown methods. This precision enhances the reproducibility and reliability of experimental results, making them a preferred choice for in-depth functional studies.
For researchers and clinicians alike, the value of SCLT1 Gene Knockout Cell Lines lies in their potential to simplify complex biological questions and drive advances in gene therapy and drug discovery. By thoroughly understanding the role of SCLT1 through these models, users can contribute to significant scientific and medical breakthroughs.
With a long-standing commitment to innovation in genetic engineering and cell biology, our company provides high-quality SCLT1 Gene Knockout Cell Lines, supported by extensive expertise and a robust backing of scientific research.
Please note that all services are for research use only. Not intended for any clinical use.
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