Gene: SCIMP
Official Full Name: SLP adaptor and CSK interacting membrane proteinprovided by HGNC
Gene Summary: This gene encodes a transmembrane adaptor protein that is expressed in antigen-presenting cells and is localized in the immunologic synapse. The encoded protein is involved in major histocompatibility complex class II signal transduction and immune synapse formation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14313 | SCIMP Knockout cell line (HEK293) | Human | SCIMP | 1:3~1:6 | Negative | Online Inquiry |
SCIMP Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to enable the study of SCIMP (Skeletal Muscle and Charcot-Marie-Tooth Diseases) gene functions through the complete disruption of the SCIMP gene. This product allows researchers to delve into the molecular mechanisms by which the SCIMP gene influences critical cellular processes, including signal transduction, immune response, and muscle physiology. The knockout mechanism utilized relies on CRISPR-Cas9 technology, which facilitates precise gene editing by creating targeted double-strand breaks in the SCIMP gene, followed by error-prone repair pathways that introduce mutations capable of disabling the gene's functionality.
The scientific importance of SCIMP Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. They provide a versatile platform for investigating the SCIMP pathway in various contexts, enabling researchers to explore its role in diseases, including autoimmune disorders and neurodegenerative conditions. Additionally, these cell lines can be employed in drug screening assays, thus accelerating the development of therapeutic agents targeting SCIMP-related pathways.
What sets SCIMP Gene Knockout Cell Lines apart from alternative models is their high specificity and reliability in mimicking the knockout phenotype. Other knockouts may exhibit off-target effects or incomplete gene disruption, leading to confounding results. SCIMP cell lines, however, ensure robust and reproducible outcomes, providing unparalleled confidence in experimental data.
For researchers and clinicians alike, the ability to utilize these specialized cell lines translates into more effective studies, facilitating breakthroughs in understanding SCIMP-related disorders and the discovery of new treatment avenues. Given our extensive expertise in developing cutting-edge biological products, our company is dedicated to providing innovative solutions that empower the scientific community and enhance research outcomes, making us a trusted partner in your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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