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SAT2 Knockout Cell Lines

Gene: SAT2

Official Full Name: spermidine/spermine N1-acetyltransferase family member 2provided by HGNC

Gene Summary: Enables diamine N-acetyltransferase activity and identical protein binding activity. Involved in polyamine metabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30942 SAT2 Knockout cell line (HeLa) Human SAT2 1:3~1:6 Negative Online Inquiry
KO30943 SAT2 Knockout cell line (HCT 116) Human SAT2 1:2~1:4 Negative Online Inquiry
KO30944 SAT2 Knockout cell line (HEK293) Human SAT2 1:3~1:6 Negative Online Inquiry
KO30945 SAT2 Knockout cell line (A549) Human SAT2 1:3~1:4 Negative Online Inquiry

Background

SAT2 Gene Knockout Cell Lines are specialized cell lines generated to lack the expression of the SAT2 gene, which encodes for the key enzyme involved in the synthesis of the neurotransmitter serotonin. These knockout models provide invaluable tools for researchers studying the role of SAT2 in various biological processes, including signal transduction, metabolic regulation, and neurobiology.

The SAT2 gene encodes the enzyme responsible for the uptake and storage of serotonin precursors, influencing serotonin levels in the body. By utilizing these knockout cell lines, scientists can dissect the mechanisms underlying serotonin's role in both physiological and pathophysiological contexts. This ability to manipulate serotonin levels provides insights into various disorders, such as depression, anxiety, and other neuropsychiatric conditions. Experimental assays conducted using SAT2 Gene Knockout Cell Lines facilitate the exploration of gene function, genetic interactions, and drug responses in a controlled setting.

What sets SAT2 Gene Knockout Cell Lines apart from traditional models is their adaptability and specificity. These cell lines are optimized for high-throughput screening and can readily be integrated into existing research workflows. Unlike standard cell lines, the complete ablation of SAT2 allows for the direct observation of changes in serotonin metabolism and signaling, subsequently leading to more accurate interpretations of experimental results.

For researchers and clinicians, the SAT2 Gene Knockout Cell Lines represent a critical resource that accelerates innovation in neuroscientific research. Their application in studying the effects of serotonin on neural circuits and behavior can help pave the way for new therapeutic approaches. Furthermore, our company brings extensive expertise in gene editing technologies, ensuring that these cell lines are produced under rigorous quality controls and customized according to user specifications.

By choosing SAT2 Gene Knockout Cell Lines, you are investing in cutting-edge research tools that can significantly enhance the understanding of serotonin's multifaceted roles in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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