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SAP30L Knockout Cell Lines

Gene: SAP30L

Official Full Name: SAP30 likeprovided by HGNC

Gene Summary: Enables several functions, including non-sequence-specific DNA binding activity, bending; phosphatidylinositol phosphate binding activity; and zinc ion binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in fibrillar center and nucleoplasm. Part of histone deacetylase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14357 SAP30L Knockout cell line (HeLa) Human SAP30L 1:3~1:6 Negative Online Inquiry
KO14358 SAP30L Knockout cell line (HCT 116) Human SAP30L 1:2~1:4 Negative Online Inquiry
KO14359 SAP30L Knockout cell line (HEK293) Human SAP30L 1:3~1:6 Negative Online Inquiry
KO14360 SAP30L Knockout cell line (A549) Human SAP30L 1:3~1:4 Negative Online Inquiry

Background

SAP30L Gene Knockout Cell Lines are genetically modified cell lines specifically designed to enable the study of the SAP30L gene's role in cellular processes and disease mechanisms. These cell lines have been engineered using CRISPR/Cas9 technology, resulting in targeted disruptions of the SAP30L gene, which encodes a protein involved in transcriptional regulation and chromatin remodeling. Through this knockout approach, researchers can elucidate the gene’s function and its impact on gene expression, cell proliferation, and differentiation.

The primary mechanism by which SAP30L knockout affects cell behavior involves altering the normal transcriptional dynamics within specific cellular pathways. By knocking out SAP30L, researchers can observe changes in the expression levels of downstream target genes, thereby dissecting its influence on cellular homeostasis and response to external stimuli. This kind of inquiry provides insights into the gene's contribution to various biological processes and its implications in diseases, including cancer and neurodegenerative disorders.

In research and clinical settings, these cell lines are invaluable tools for functional genomics studies, drug development, and disease modeling. They are particularly beneficial for identifying potential therapeutic targets and understanding the molecular underpinnings of pathologies related to the SAP30L gene. Unlike traditional methods that may rely on non-specific inhibitors or broad-spectrum genetic alterations, SAP30L Gene Knockout Cell Lines offer a precision-based and direct approach, rendering more reliable and reproducible results.

The unique selling points of our SAP30L Gene Knockout Cell Lines reside in their specificity, ease of use, and compatibility with standard laboratory techniques. Researchers can utilize them with minimal additional modification, allowing for a streamlined workflow. Moreover, our cell lines are extensively validated for performance, ensuring that users can trust the results they generate to be both accurate and relevant.

For researchers, clinicians, and biotechnologists, the SAP30L Gene Knockout Cell Lines represent a significant advancement in understanding the complexities of gene function and interaction within cellular contexts. Our company, a leader in the field of genetic engineering and cell biology, is committed to providing high-quality biological products that facilitate innovation and discovery in life sciences. With our expertise, we equip professionals to pursue their research goals and drive forward essential breakthroughs in health and disease management.

Please note that all services are for research use only. Not intended for any clinical use.

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