Gene: S100A10
Official Full Name: S100 calcium binding protein A10provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01949 | S100A10 Knockout cell line (HeLa) | Human | S100A10 | 1:3~1:6 | Negative | Online Inquiry |
KO01950 | S100A10 Knockout cell line (HCT 116) | Human | S100A10 | 1:2~1:4 | Negative | Online Inquiry |
KO01951 | S100A10 Knockout cell line (HEK293) | Human | S100A10 | 1:3~1:6 | Negative | Online Inquiry |
KO01952 | S100A10 Knockout cell line (A549) | Human | S100A10 | 1:3~1:4 | Negative | Online Inquiry |
S100A10 Gene Knockout Cell Lines represent a groundbreaking innovation in cellular biology, specifically tailored for research requiring the exploration of the S100A10 protein's function and its role in various physiological and pathological processes. These cell lines have undergone precise gene-editing techniques to knockout the S100A10 gene, effectively eliminating the expression of this calcium-binding protein. This allows researchers to study the downstream effects of the absence of S100A10, which is implicated in cellular signaling, migration, and tumor progression.
The key mechanism of action involves the disruption of pathways regulated by S100A10, such as those linked to cell stress responses and inflammation. By utilizing these knockout cell lines, researchers can precisely investigate the functional implications of S100A10 deletion on cell behavior and interaction with other signaling molecules. This contributes significant insights into conditions such as cancer, neurodegenerative diseases, and autoimmune disorders, where S100A10 is often found to be dysregulated.
The scientific importance of these cell lines lies in their diverse applications across research and clinical settings. Researchers can leverage the S100A10 knockout model for drug screening, biomarker discovery, and understanding disease mechanisms. This innovative tool is particularly valuable as it facilitates the identification of potential therapeutic targets aimed at restoring normal cellular functions disturbed in various diseases.
Compared to conventional cell models, S100A10 Gene Knockout Cell Lines offer unparalleled specificity and reliability, enabling a high degree of confidence in experimental outcomes. By obtaining precise knockout models, researchers no longer need to rely on pharmacological inhibitors, which may have off-target effects and confound results.
In summary, these cell lines are an essential asset for researchers looking to unravel the complexities of S100A10. They provide an invaluable resource for advancing our understanding of relevant biological processes, ultimately guiding therapeutic developments. Our company, a leader in biotechnological research tools, is committed to providing high-quality, reliable, and innovative products that empower scientific discovery and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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