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RXYLT1 Knockout Cell Lines

Gene: RXYLT1

Official Full Name: ribitol xylosyltransferase 1provided by HGNC

Gene Summary: This gene encodes a type II transmembrane protein that is thought to have glycosyltransferase function. Mutations in this gene result in cobblestone lissencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31975 RXYLT1 Knockout cell line (HeLa) Human RXYLT1 1:3~1:6 Negative Online Inquiry
KO31976 RXYLT1 Knockout cell line (HCT 116) Human RXYLT1 1:2~1:4 Negative Online Inquiry
KO31977 RXYLT1 Knockout cell line (HEK293) Human RXYLT1 1:3~1:6 Negative Online Inquiry
KO31978 RXYLT1 Knockout cell line (A549) Human RXYLT1 1:3~1:4 Negative Online Inquiry

Background

RXYLT1 Gene Knockout Cell Lines are precision-engineered cellular models that have undergone targeted gene disruption of the RXYLT1 gene, which encodes a crucial enzyme involved in the biosynthesis of glycosylated proteins. By utilizing advanced CRISPR/Cas9 gene-editing technology, these knockout cell lines provide researchers with robust tools to investigate the biological roles of the RXYLT1 gene and its implications in various physiological and pathological contexts.

The key function of the RXYLT1 Gene Knockout Cell Lines lies in their ability to facilitate studies on the biological consequences of RXYLT1 disruption. By eliminating the expression of this gene, researchers can assess changes in glycosylation patterns, protein stability, and cellular responses, allowing for a deeper understanding of how RXYLT1 influences processes such as cell signaling, differentiation, and pathogenesis. This functional insight is vital in the exploration of diseases potentially associated with aberrant glycosylation, including cancer and genetic disorders.

The scientific significance of these knockout cell lines extends to both research and clinical applications. In academic laboratories, they serve as indispensable tools for elucidating the molecular mechanisms underlying various diseases, while in clinical settings, they may aid in developing novel therapeutic strategies aimed at correcting glycosylation defects.

What sets RXYLT1 Gene Knockout Cell Lines apart from alternative models is their unparalleled specificity and precision. Unlike traditional models that may produce heterogeneous results due to off-target effects or incomplete gene disruption, our knockout cell lines ensure a uniform genetic background. Additionally, these cell lines have undergone rigorous validation processes, confirming the complete knockout of the RXYLT1 gene and reinstating confidence in experimental outcomes.

The value of RXYLT1 Gene Knockout Cell Lines to researchers and clinicians is undeniable. They enable high-throughput screening, offer insights into glycosylation-related disorders, and foster the development of targeted therapies, thereby advancing our understanding and treatment options for complex diseases.

As a leader in the field of genetic engineering and cellular biology, our company is committed to delivering high-quality biological products that empower researchers and healthcare professionals. Our expertise and dedication to innovation ensure that our customers receive reliable and effective tools for their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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