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RRAS Knockout Cell Lines

Gene: RRAS

Official Full Name: RAS relatedprovided by HGNC

Gene Summary: The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08993 RRAS Knockout cell line (HeLa) Human RRAS 1:3~1:6 Negative Online Inquiry
KO08994 RRAS Knockout cell line (HCT 116) Human RRAS 1:2~1:4 Negative Online Inquiry
KO08995 RRAS Knockout cell line (HEK293) Human RRAS 1:3~1:6 Negative Online Inquiry
KO08996 RRAS Knockout cell line (A549) Human RRAS 1:3~1:4 Negative Online Inquiry

Background

RRAS Gene Knockout Cell Lines are specifically engineered cellular systems designed to investigate the functional role of the RRAS gene in various biological processes. Through advanced CRISPR/Cas9 knockout technology, these cell lines offer a precise suppression of RRAS gene expression, allowing researchers to study the downstream effects of RRAS deficiency on cellular behavior, signaling pathways, and disease mechanisms.

The primary function of RRAS is to encode a small GTPase involved in the regulation of several critical cellular functions, including proliferation, differentiation, and apoptosis. By utilizing these knockout cell lines, researchers can elucidate the role of RRAS in oncogenic signaling and other pathological conditions. The mechanisms of action are grounded in the disruption of RRAS's signaling cascade, which subsequently affects RAS activation pathways, leading to altered cellular responses that are crucial in understanding tumor biology and other RRAS-related diseases.

The scientific importance of RRAS Gene Knockout Cell Lines lies in their ability to provide insights into cancer biology, especially in the context of cellular transformation and metastatic behavior. These cell lines facilitate high-throughput screening and can be instrumental in drug discovery efforts that target RRAS-associated signaling pathways, making them invaluable in both research and clinical applications.

Compared to alternative models, such as transient transfection systems or conventional RNA interference, our knockout cell lines offer a stable and reproducible model for long-term studies. They eliminate the variability often associated with transiently knocked down genes and provide more reliable data over a protracted experimental timeline.

For researchers and clinicians seeking to deepen their understanding of RRAS's role in health and disease, these cell lines offer a unique opportunity to explore potential therapeutic targets. The precision of our RRAS Gene Knockout Cell Lines allows for streamlined research workflows, which can enhance productivity and accelerate the translation of findings into applications.

With our extensive expertise in genetic engineering and a portfolio of high-quality biological products, we are committed to advancing the field of molecular biology and empowering researchers in their quest for innovative solutions in health and disease management.

Please note that all services are for research use only. Not intended for any clinical use.

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