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RNLS Knockout Cell Lines

Gene: RNLS

Official Full Name: renalase, FAD dependent amine oxidaseprovided by HGNC

Gene Summary: Enables several functions, including NADH binding activity; epinephrine binding activity; and monoamine oxidase activity. Involved in negative regulation of blood pressure and negative regulation of heart rate. Located in extracellular region. Implicated in essential hypertension and hypertension. Biomarker of end stage renal disease. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14445 RNLS Knockout cell line (HeLa) Human RNLS 1:3~1:6 Negative Online Inquiry
KO14446 RNLS Knockout cell line (A549) Human RNLS 1:3~1:4 Negative Online Inquiry

Background

RNLS Gene Knockout Cell Lines are precisely engineered cellular models designed to enable researchers to study the functional role of the RNLS gene in biological processes. Utilizing advanced CRISPR-Cas9 gene editing technology, these cell lines have been created through the targeted disruption of RNLS, effectively removing its expression. By creating a specific knockout of the RNLS gene, these cell lines permit in-depth exploration of cellular pathways influenced by RNLS, providing critical insights into functions such as signal transduction, metabolic regulation, and developmental processes.

The primary function of RNLS Gene Knockout Cell Lines lies in their ability to serve as a platform for functional genomics studies. Researchers can investigate the downstream effects of RNLS loss on various cellular functions, thereby elucidating its roles in pathological states, such as cancer and neurodegenerative diseases. The knockout model allows for the comprehensive analysis of gene interactions and regulatory networks, facilitating a better understanding of cellular dynamics in health and disease.

The scientific importance of these cell lines cannot be overstated. In research and clinical settings, they serve as essential tools for drug discovery, target validation, and biomarker identification. Leveraging these models can significantly enhance the efficiency of preclinical trials by providing robust data on gene function and therapeutic responses.

Compared to existing alternatives, RNLS Gene Knockout Cell Lines offer unparalleled specificity and precision due to their CRISPR-Cas9 origin, making them superior for targeted gene disruption. This specificity reduces the risk of off-target effects often associated with traditional knockout methods, thereby ensuring the reliability of experimental outcomes.

For researchers and clinicians, investing in RNLS Gene Knockout Cell Lines means gaining access to high-quality models that can drive innovation in translational research and therapeutic development. Their robustness and versatility make them invaluable assets for both basic research and applied sciences.

Our company is dedicated to advancing biological research by offering high-quality, precise genetic models such as RNLS Gene Knockout Cell Lines. With years of expertise in genetic engineering and cell line development, we strive to empower scientists with tools that enhance their research capabilities and contribute to advancements in the field.

Please note that all services are for research use only. Not intended for any clinical use.

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