Gene: RNF32
Official Full Name: ring finger protein 32provided by HGNC
Gene Summary: The protein encoded by this gene contains two RING ring finger motifs. RING finger motifs are present in a variety of functionally distinct proteins and are known to be involved in protein-DNA or protein-protein interactions. This gene was found to be expressed during spermatogenesis, most likely in spermatocytes and/or in spermatids. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25585 | RNF32 Knockout cell line (HCT 116) | Human | RNF32 | 1:2~1:4 | Negative | Online Inquiry |
KO25586 | RNF32 Knockout cell line (HEK293) | Human | RNF32 | 1:3~1:6 | Negative | Online Inquiry |
KO25587 | RNF32 Knockout cell line (A549) | Human | RNF32 | 1:3~1:4 | Negative | Online Inquiry |
RNF32 Gene Knockout Cell Lines are specially engineered cellular models that have undergone targeted gene disruption of the RNF32 gene, which encodes a protein implicated in various cellular processes, including protein ubiquitination and regulation of gene expression. These knockout cell lines are pivotal tools for studying the functional consequences of RNF32 loss, enabling researchers to delve into the gene’s role in oncogenesis, cellular signaling pathways, and disease mechanisms.
The primary function of RNF32 lies in its involvement in ubiquitin-mediated proteolysis, a crucial pathway for maintaining cellular homeostasis. By knocking out this gene, the mechanisms governing cellular proliferation, apoptosis, and stress responses can be elucidated. Consequently, these cell lines facilitate in-depth assays, including cellular growth analysis, protein interaction studies, and drug screening, thereby fostering a greater understanding of therapeutic targets in cancer and other diseases.
The scientific importance of RNF32 Gene Knockout Cell Lines is underscored by their diverse applications in both research and clinical settings. Researchers can utilize these cell lines to investigate the downstream effects of RNF32 disruption on cellular pathways, providing insights into tumor biology and potential biomarker development. Clinicians aiming to develop novel therapeutic strategies can leverage findings derived from these models to design targeted treatments that inhibit or modify the activity of pathways influenced by RNF32.
What sets RNF32 Gene Knockout Cell Lines apart from traditional models is their specificity and reliability. Unlike unspecific gene silencing approaches, these knockout lines provide a complete absence of the RNF32 protein, ensuring that any observed phenotypic alterations can be directly attributed to the loss of this gene. Furthermore, they are generated through state-of-the-art CRISPR/Cas9 technology, ensuring high fidelity and reproducibility.
For researchers and clinicians alike, these cell lines represent an invaluable asset, offering the precision needed to dissect complex biological processes and facilitate advancements in therapeutic development. Our company, with extensive expertise in gene editing technologies and cellular model systems, is committed to delivering high-quality biological tools that empower scientific breakthroughs. We offer unparalleled support and guidance to ensure that researchers can maximize the potential of our RNF32 Gene Knockout Cell Lines in their studies.
Please note that all services are for research use only. Not intended for any clinical use.
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