Home / RNF227 Knockout Cell Lines

RNF227 Knockout Cell Lines

Gene: RNF227

Official Full Name: ring finger protein 227provided by HGNC

Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14447 RNF227 Knockout cell line (HeLa) Human RNF227 1:3~1:6 Negative Online Inquiry
KO14448 RNF227 Knockout cell line (HEK293) Human RNF227 1:3~1:6 Negative Online Inquiry
KO14449 RNF227 Knockout cell line (A549) Human RNF227 1:3~1:4 Negative Online Inquiry

Background

RNF227 Gene Knockout Cell Lines consist of genetically modified human cell lines in which the RNF227 gene has been systematically disrupted. This process, typically facilitated by CRISPR-Cas9 technology, allows for the study of gene function by creating a loss-of-function model that provides crucial insights into the role of RNF227 in cellular processes. The knockout of RNF227 facilitates comprehensive analyses of its downstream effects on signaling pathways, gene expression, and cellular phenotypes, enhancing our understanding of the molecular mechanisms underlying various biological phenomena.

The key function of RNF227 is its involvement in protein ubiquitination, a post-translational modification that regulates protein stability, localization, and activity. By utilizing RNF227 Knockout Cell Lines, researchers can investigate the consequences of RNF227 absence on ubiquitin-mediated signaling pathways, potentially uncovering novel therapeutic targets for diseases linked to aberrant protein degradation, such as cancer and neurodegenerative disorders.

This product holds significant scientific importance as it serves as a valuable tool in both basic research and clinical settings. In translational research, understanding the role of RNF227 could contribute to the development of targeted therapies and biomarker discovery for various diseases. Moreover, these cell lines can be utilized in screening assays to identify compounds that modulate RNF227-related pathways, driving therapeutic innovation.

One of the unique selling points of our RNF227 Gene Knockout Cell Lines is their precise gene editing, which provides a high-specificity model compared to traditional knockdown methods. The authentic knockout eliminates the possibility of residual gene activity, thereby granting researchers a clearer understanding of the complete absence of RNF227. Additionally, these cell lines are compatible with a wide range of experimental setups, making them versatile tools for diverse applications from pharmacological studies to mechanistic investigations.

For researchers, clinicians, and drug developers, the RNF227 Gene Knockout Cell Lines represent a critical advancement in genetic research, paving the way for breakthroughs in understanding complex biological systems. At [Your Company Name], we pride ourselves on our expertise in genetic engineering and our commitment to providing tools that empower scientific discovery and innovation. Our focus on quality and reliability ensures that researchers can trust our products to facilitate groundbreaking discoveries in the field of cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.