Gene: RND3
Official Full Name: Rho family GTPase 3provided by HGNC
Gene Summary: This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38933 | RND3 Knockout cell line (HeLa) | Human | RND3 | 1:3~1:6 | Negative | Online Inquiry |
KO38934 | RND3 Knockout cell line (HCT 116) | Human | RND3 | 1:2~1:4 | Negative | Online Inquiry |
KO38935 | RND3 Knockout cell line (HEK293) | Human | RND3 | 1:3~1:6 | Negative | Online Inquiry |
KO38936 | RND3 Knockout cell line (A549) | Human | RND3 | 1:3~1:4 | Negative | Online Inquiry |
RND3 Gene Knockout Cell Lines are genetically modified cell lines in which the RND3 gene has been intentionally disrupted through a process known as gene knockout. This targeted genetic alteration allows researchers to study the specific functions and interactions of the RND3 protein—the role of which in cellular processes such as cytoskeletal dynamics, cell migration, and signaling pathways has been increasingly recognized. The RND3 protein, part of the Rho family of GTPases, plays a crucial role in regulating various cellular functions, making these cell lines invaluable for dissecting the pathways in which RND3 is involved.
These knockout cell lines operate through the complete removal of the RND3 gene’s expression, leading to observable phenotypic changes that can be quantitatively analyzed. Researchers utilize these models to investigate the downstream effects of RND3 absence on cellular behavior, including proliferation, differentiation, and stress response. The insights garnered from these investigations are pivotal in elucidating the gene’s role in diseases such as cancer and developmental disorders, thereby enhancing our understanding of its therapeutic potential.
The scientific importance of RND3 Gene Knockout Cell Lines extends to both research and clinical applications. They serve as a robust platform for drug screening, mechanistic studies, and the identification of novel therapeutic targets. Additionally, they provide a reliable model for studying the efficacy and safety of new compounds, which is crucial for advancing drug development in academic and pharmaceutical settings.
What sets our RND3 Gene Knockout Cell Lines apart from alternatives is their high specificity and validated reliability, ensuring reproducible results across multiple experimental setups. Furthermore, as these lines are developed using stringent quality controls and optimized protocols, they can significantly enhance the efficiency of research workflows, effectively saving time and resources for researchers.
For researchers and clinicians alike, the availability of RND3 Gene Knockout Cell Lines opens new avenues for hypothesis-driven research and improves the capacity to identify potential avenues for clinical intervention. Our company is committed to advancing scientific discovery through high-quality biological products, backed by a dedicated team of experts focused on innovation and precision in genetic modifications. By choosing our products, users are not only selecting cutting-edge technology but also partnering with a leader in the field of genetic engineering.
Please note that all services are for research use only. Not intended for any clinical use.
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