Gene: RLF
Official Full Name: RLF zinc fingerprovided by HGNC
Gene Summary: Predicted to enable DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of heterochromatin formation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35608 | RLF Knockout cell line (HeLa) | Human | RLF | 1:3~1:6 | Negative | Online Inquiry |
KO35609 | RLF Knockout cell line (HCT 116) | Human | RLF | 1:2~1:4 | Negative | Online Inquiry |
KO35610 | RLF Knockout cell line (HEK293) | Human | RLF | 1:3~1:6 | Negative | Online Inquiry |
KO35611 | RLF Knockout cell line (A549) | Human | RLF | 1:3~1:4 | Negative | Online Inquiry |
RLF Gene Knockout Cell Lines are genetically engineered cell lines designed to disable specific genes, enabling researchers to study the resulting phenotypic variations and gain insights into gene function and regulation. Through a process known as CRISPR-Cas9 gene editing or other knockout techniques, these cell lines have been meticulously developed to ensure precise gene disruption, offering a robust platform for functional genomics and cellular biology research.
The key mechanism of action involves the targeted deletion of specific gene sequences, leading to a loss of gene expression. This function allows scientists to observe the consequences of gene loss, including alterations in cell behavior, signaling pathways, and metabolic processes. By elucidating the roles of genes in cellular function, RLF Gene Knockout Cell Lines facilitate investigations into various biological phenomena, such as disease mechanisms, drug responses, and developmental processes.
The scientific importance of these cell lines cannot be overstated, as they serve as essential tools in both research and clinical settings. They provide a means to explore genetic contributions to diseases like cancer, neurodegenerative disorders, and autoimmune conditions, thus opening pathways for therapeutic development and personalized medicine approaches.
Compared to alternative models, RLF Gene Knockout Cell Lines are uniquely validated for specificity and efficiency, ensuring minimal off-target effects that could confound experimental results. Additionally, these cell lines come with detailed characterizations and data sheets, empowering researchers with the knowledge necessary to select appropriate models for their studies.
For researchers and clinicians, the value of RLF Gene Knockout Cell Lines lies not only in their ability to advance understanding of gene functions but also in their potential to inform clinical innovations, leading to novel therapeutic strategies and improved patient outcomes. Our company has extensive experience in producing high-quality biological products, ensuring that our offerings, including RLF Gene Knockout Cell Lines, meet the rigorous needs of the scientific community. With a commitment to excellence in research tools, we empower scientists to unlock new discoveries in genetics and cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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