Gene: RIT1
Official Full Name: Ras like without CAAX 1provided by HGNC
Gene Summary: This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05264 | RIT1 Knockout cell line (HeLa) | Human | RIT1 | 1:3~1:6 | Negative | Online Inquiry |
KO05265 | RIT1 Knockout cell line (HCT 116) | Human | RIT1 | 1:2~1:4 | Negative | Online Inquiry |
KO05266 | RIT1 Knockout cell line (HEK293) | Human | RIT1 | 1:3~1:6 | Negative | Online Inquiry |
KO05267 | RIT1 Knockout cell line (A549) | Human | RIT1 | 1:3~1:4 | Negative | Online Inquiry |
The RIT1 Gene Knockout Cell Lines are specialized research tools designed for studying the role and function of the RIT1 gene, which encodes a small GTPase involved in cellular signaling pathways crucial for proliferation, differentiation, and survival. These cell lines are engineered to have a targeted deletion of the RIT1 gene, allowing researchers to explore the consequences of RIT1 loss on various cellular processes and disease pathogenesis, particularly in cancer and developmental disorders.
Functionally, these knockout cell lines provide a unique platform to investigate the signaling cascades affected by RIT1, as well as its interactions with downstream effectors. By eliminating RIT1, researchers can utilize these cell lines to elucidate the molecular mechanisms that drive RIT1-associated diseases or to evaluate potential therapeutic interventions that aim to restore normal cellular function.
The scientific importance of RIT1 Gene Knockout Cell Lines extends into both basic research and clinical applications. In cancer biology, for instance, understanding the pathways disrupted by RIT1 loss can lead to the identification of novel biomarkers and therapeutic targets. In clinical settings, these models can facilitate drug development and personalized medicine approaches by informing pharmacological responses based on the genetic makeup of tumors.
What sets our RIT1 Gene Knockout Cell Lines apart from alternatives is their high fidelity and reproducibility, allowing for consistent results across experiments. Additionally, these cell lines are validated for their growth patterns and expression profiles, ensuring that they support a wide range of experimental designs, from high-throughput screenings to detailed mechanistic studies.
For researchers and clinicians, these cell lines represent an invaluable resource. Their integration into experimental workflows can accelerate discovery and enhance the understanding of RIT1-related biology, empowering scientists to translate their findings into real-world applications that improve patient outcomes.
Our company prides itself on delivering high-quality biological products backed by rigorous scientific validation and expertise in cell line development. With a commitment to advancing research tools, we help scientists explore the frontiers of molecular biology effectively and efficiently.
Please note that all services are for research use only. Not intended for any clinical use.
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