Home / RIMS3 Knockout Cell Lines

RIMS3 Knockout Cell Lines

Gene: RIMS3

Official Full Name: regulating synaptic membrane exocytosis 3provided by HGNC

Gene Summary: Predicted to enable transmembrane transporter binding activity. Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in several processes, including regulated exocytosis; regulation of synapse organization; and regulation of synaptic vesicle exocytosis. Predicted to be located in presynaptic active zone. Predicted to be active in several cellular components, including postsynaptic cytosol; presynaptic active zone cytoplasmic component; and presynaptic membrane. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32763 RIMS3 Knockout cell line (HCT 116) Human RIMS3 1:2~1:4 Negative Online Inquiry
KO32764 RIMS3 Knockout cell line (HEK293) Human RIMS3 1:3~1:6 Negative Online Inquiry
KO32765 RIMS3 Knockout cell line (A549) Human RIMS3 1:3~1:4 Negative Online Inquiry

Background

RIMS3 Gene Knockout Cell Lines are genetically engineered cell models designed to facilitate the study of RIMS3 (Robust Interaction between Microtubules and Syntaxin 3) function in cellular processes. These cell lines serve as a powerful tool for researchers aiming to investigate the impact of RIMS3 loss-of-function on neurotransmitter release and synaptic vesicle dynamics, thereby advancing our understanding of neurobiology and synaptic transmission.

The core function of RIMS3 revolves around its role in modulating the release of neurotransmitters at the synapse, which is essential for effective neuronal communication. Through mechanisms that involve vesicle docking and fusion, RIMS3 is critical for maintaining synaptic efficacy. By utilizing RIMS3 Gene Knockout Cell Lines, researchers can elucidate the specific pathways and interactions that are dependent on RIMS3, shedding light on its involvement in various neurological disorders.

The scientific importance of these knockout cell lines is profound, particularly for research in neurodevelopmental and neurodegenerative diseases where synaptic malfunction is a prominent feature. In clinical settings, understanding the roles of RIMS3 may pave the way for novel therapeutic interventions, making these cell lines an invaluable resource for both basic and applied research.

Compared to traditional wild-type models, RIMS3 Gene Knockout Cell Lines offer a significant advantage by providing a clear genetic background to study the functional consequences of RIMS3 absence. This specificity allows for more accurate modeling of disease-related phenotypes and accelerated discovery of potential drug targets.

For researchers and clinicians, the value of RIMS3 Gene Knockout Cell Lines lies in their potential to transform theoretical knowledge into practical applications that could lead to breakthroughs in treatment strategies. By harnessing these sophisticated cell models, users can delve deeper into the complexities of synaptic function and dysfunction.

Our company specializes in advanced genetic engineering solutions, providing high-quality and validated cell lines that meet rigorous research standards. With our commitment to scientific excellence, we empower the research community to push the boundaries of knowledge in molecular and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.