Gene: RGS9
Official Full Name: regulator of G protein signaling 9provided by HGNC
Gene Summary: This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33869 | RGS9 Knockout cell line (HCT 116) | Human | RGS9 | 1:2~1:4 | Negative | Online Inquiry |
KO33870 | RGS9 Knockout cell line (A549) | Human | RGS9 | 1:3~1:4 | Negative | Online Inquiry |
RGS9 Gene Knockout Cell Lines represent a cutting-edge innovation in genetic research, engineered to facilitate the study of the RGS9 gene's role in critical cellular processes. RGS9, or Regulator of G Protein Signaling 9, is known for its involvement in modulating G-protein signaling pathways, impacting various physiological responses, including sensory perception and neuronal signaling. These knockout cell lines are developed using advanced CRISPR-Cas9 techniques, ensuring precise gene editing that effectively disables the RGS9 gene, allowing researchers to investigate the resulting phenotypic changes and the underlying mechanisms.
The key functions of RGS9 encompass modulating the lifetime of G-protein-coupled receptor signaling, influencing signal transduction duration and intensity in cells. This foundational mechanism underscores RGS9's role in physiological processes in the central nervous system and its contributions to disorders like schizophrenia and substance abuse. By utilizing RGS9 knockout cell lines, researchers can explore the implications of this regulation in diverse experimental conditions.
The scientific importance of these cell lines extends to their application in research contexts, such as pharmacology, neuroscience, and genetic diseases. With RGS9 playing a pivotal role in signal transduction, understanding its pathways through these knockout models has profound implications for drug development and the understanding of receptor biology. Moreover, these cell lines provide a unique tool for elucidating the complex interactions of intracellular signaling pathways, contributing to breakthroughs in identifying new therapeutic targets.
One of the standout advantages of RGS9 Gene Knockout Cell Lines is their specificity and reliability compared to other knockout methods that may not guarantee complete gene inactivation. By eliminating the RGS9 gene entirely, scientists can draw more accurate conclusions regarding gene function and expression, reducing experimental variability. Additionally, the ease of culturing and the compatibility with high-throughput screening make these cell lines an invaluable resource for labs focused on drug discovery.
For researchers and clinicians dedicated to exploring the nuances of gene function, these knockout cell lines are indispensable. They provide unparalleled opportunities to translate foundational research into clinically relevant applications, bridging the gap between genetics and diverse medical fields. Our company, renowned for its expertise in producing high-quality biological products, is committed to empowering scientists with reliable tools, such as the RGS9 Gene Knockout Cell Lines, that drive innovation and discovery in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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