Gene: RGS5
Official Full Name: regulator of G protein signaling 5provided by HGNC
Gene Summary: This locus represents naturally occurring readthrough transcription between the neighboring LOC127814295 (uncharacterized LOC127814295) and RGS5 (regulator of G-protein signaling 5) genes on chromosome 1. Some variants of the readthrough transcript encode novel proteins with unique N-termini. [provided by RefSeq, Nov 2022]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34138 | RGS5 Knockout cell line (HeLa) | Human | RGS5 | 1:3~1:6 | Negative | Online Inquiry |
KO34139 | RGS5 Knockout cell line (HCT 116) | Human | RGS5 | 1:2~1:4 | Negative | Online Inquiry |
KO34140 | RGS5 Knockout cell line (HEK293) | Human | RGS5 | 1:3~1:6 | Negative | Online Inquiry |
KO34141 | RGS5 Knockout cell line (A549) | Human | RGS5 | 1:3~1:4 | Negative | Online Inquiry |
RGS5 Gene Knockout Cell Lines are specifically engineered cellular models that lack the expression of the RGS5 gene, which encodes a regulator of G protein signaling proteins involved in various physiological processes and pathophysiological conditions. These knockout cell lines provide researchers with invaluable tools for studying the role of RGS5 in cellular signaling pathways, cardiovascular diseases, cancer, and neurological disorders. By elucidating the molecular mechanisms impacted by RGS5 deletion, scientists can uncover pivotal insights into the regulation of cell proliferation, differentiation, and apoptosis.
The primary function of RGS5 is to act as a negative regulator of G protein-coupled receptor (GPCR) signaling by enhancing the intrinsic GTPase activity of G proteins. The RGS5 knockout cell lines facilitate direct examinations of downstream effects upon GPCR activation, allowing researchers to discern the consequences of altered signaling dynamics. This can lead to advancements in therapeutic interventions targeted at restoring normal signaling pathways that may be dysregulated in disease states.
The scientific importance of RGS5 Gene Knockout Cell Lines extends into both research and clinical settings. Their application ranges from basic biological research to drug discovery and development, particularly in fields such as oncology, neurology, and cardiovascular health. These models not only provide a platform for functional studies but also enable high-throughput screening for potential drug candidates that can modulate RGS5-related pathways.
What sets RGS5 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Traditional models may lack the complete ablation of RGS5 function, potentially confounding study results. Our knockout cell lines ensure that the absence of RGS5 is well-characterized and that any observed phenotypic changes can be specifically attributed to this genetic modification.
For researchers and clinicians, the value of RGS5 Gene Knockout Cell Lines lies in their capacity to drive innovative discoveries and therapeutic solutions. By utilizing these advanced cell lines, users can significantly enhance the precision and relevance of their studies, pushing the frontiers of biomedical research.
Our company is dedicated to delivering high-quality biological products, backed by robust scientific expertise and a commitment to advancing research in critical health domains. By integrating cutting-edge technology with profound knowledge of genetic regulation, we strive to support researchers in unlocking the complexities of biological systems.
Please note that all services are for research use only. Not intended for any clinical use.
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