Gene: RFX7
Official Full Name: regulatory factor X7provided by HGNC
Gene Summary: RFX7 is a member of the regulatory factor X (RFX) family of transcription factors (see RFX1, MIM 600006) (Aftab et al., 2008 [PubMed 18673564]).[supplied by OMIM, Mar 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14580 | RFX7 Knockout cell line (HeLa) | Human | RFX7 | 1:3~1:6 | Negative | Online Inquiry |
KO14581 | RFX7 Knockout cell line (HCT 116) | Human | RFX7 | 1:2~1:4 | Negative | Online Inquiry |
KO14582 | RFX7 Knockout cell line (HEK293) | Human | RFX7 | 1:3~1:6 | Negative | Online Inquiry |
KO14583 | RFX7 Knockout cell line (A549) | Human | RFX7 | 1:3~1:4 | Negative | Online Inquiry |
RFX7 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to have a disruption in the RFX7 gene, which plays a crucial role in the regulation of gene expression in the immune response. By employing CRISPR-Cas9 technology, these cell lines facilitate the study of RFX7 function and its consequential effects on various biological processes, particularly those related to immune cell development and activity. The successful knockout of this gene allows researchers to investigate the pathways associated with RFX7, providing insights into its involvement in complex diseases and immune disorders.
The primary mechanism of action involves the complete deletion of coding sequences, resulting in the loss of RFX7 protein expression. This leads to altered cellular signaling and prompts researchers to elucidate the downstream effects on gene regulation and immune responses. Such functional studies are critical to understanding how disruptions in RFX7 can contribute to disease pathology, thereby opening avenues for potential therapeutic interventions and biomarker development.
The scientific importance of RFX7 Gene Knockout Cell Lines extends to their applications in both basic research and preclinical studies. They enable scientists to create models that simulate diseases, thus facilitating drug testing and the exploration of novel therapeutic agents. Additionally, they provide a valuable resource for the study of gene regulatory networks, contributing to advancements in gene therapy and precision medicine.
One of the unique selling points of RFX7 Gene Knockout Cell Lines compared to conventional models is the precision of the gene editing technology used, which minimizes off-target effects and enhances reproducibility in experimental outcomes. Furthermore, these cell lines are readily adaptable for high-throughput screening applications, allowing for efficient exploration of genetic interactions and drug responses.
Researchers and clinicians targeting the intricacies of immune regulation will find these knockout cell lines invaluable for their ability to offer more accurate models of biological systems. Through the use of RFX7 Gene Knockout Cell Lines, they can advance their understanding of immune mechanisms and discover new therapies to combat diseases. Our company specializes in providing high-quality biological products with a rigorous focus on scientific innovation and integrity, ensuring that our clients have access to cutting-edge tools necessary for groundbreaking research.
Please note that all services are for research use only. Not intended for any clinical use.
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