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RFX3 Knockout Cell Lines

Gene: RFX3

Official Full Name: regulatory factor X3provided by HGNC

Gene Summary: This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35629 RFX3 Knockout cell line (HeLa) Human RFX3 1:3~1:6 Negative Online Inquiry
KO35630 RFX3 Knockout cell line (HCT 116) Human RFX3 1:2~1:4 Negative Online Inquiry
KO35631 RFX3 Knockout cell line (HEK293) Human RFX3 1:3~1:6 Negative Online Inquiry
KO35632 RFX3 Knockout cell line (A549) Human RFX3 1:3~1:4 Negative Online Inquiry

Background

RFX3 Gene Knockout Cell Lines are genetically engineered cell models that have undergone targeted gene disruption of the RFX3 gene, which encodes a transcription factor involved in the genetic regulation of various biological processes. These cell lines provide researchers with a powerful tool for elucidating the specific roles of RFX3 in cellular function, development, and disease mechanisms. By creating a knockout system, researchers can study the downstream effects of the loss of RFX3, allowing for the exploration of its involvement in immune response, cell signaling pathways, and potential links to various pathologies.

The key mechanism underlying RFX3 Gene Knockout Cell Lines lies in their ability to replicate physiological conditions while lacking the functional RFX3 gene. This allows for precise manipulation of cellular environments, making it possible to observe changes in gene expression, protein activity, and cellular behavior in response to the absence of RFX3. These alterations can significantly enhance the understanding of related molecular pathways and lead to insights into conditions such as immune deficiencies and cancers.

In terms of scientific importance, these cell lines have wide applications in both research and clinical settings, including but not limited to functional genomics, drug screening, and the development of novel therapeutic strategies. Their use in experimental designs accelerates the discovery of biomarkers and potential targets for disease intervention, providing a solid foundation for translational research.

Compared to alternative models, such as wild-type or non-specific knockout lines, RFX3 Gene Knockout Cell Lines offer a degree of specificity and reproducibility that is unparalleled. This ensures that researchers can confidently attribute observed phenotypes to the absence of the RFX3 gene, thus enhancing the reliability of experimental outcomes.

The value of RFX3 Gene Knockout Cell Lines extends beyond basic research; they are instrumental for clinicians and pharmaceutical companies seeking to develop targeted therapies and personalized medicine approaches. By utilizing these advanced cell lines, scientists can create a more accurate picture of how RFX3 influences various biological systems and how its modulation might be harnessed therapeutically.

Our company is committed to providing high-quality genetic models, and our RFX3 Gene Knockout Cell Lines epitomize our dedication to facilitating scientific inquiry and innovation. With a focus on precision and reliability, our offerings are designed to support researchers in their quest for discovery and advancement in the biological sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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