Gene: REEP1
Official Full Name: receptor accessory protein 1provided by HGNC
Gene Summary: This gene encodes a mitochondrial protein that functions to enhance the cell surface expression of odorant receptors. Mutations in this gene cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20622 | REEP1 Knockout cell line (HeLa) | Human | REEP1 | 1:3~1:6 | Negative | Online Inquiry |
KO20623 | REEP1 Knockout cell line (HCT 116) | Human | REEP1 | 1:2~1:4 | Negative | Online Inquiry |
KO20624 | REEP1 Knockout cell line (HEK293) | Human | REEP1 | 1:3~1:6 | Negative | Online Inquiry |
REEP1 Gene Knockout Cell Lines represent a groundbreaking tool for molecular biologists and genetic researchers focused on unraveling the complexities of neurodegenerative diseases and cell signaling pathways. These cell lines are engineered to specifically eliminate the REEP1 gene, a critical element implicated in diseases such as hereditary spastic paraplegia (HSP). By knocking out this gene, researchers can meticulously investigate the cellular mechanisms and pathways that contribute to the pathological features associated with its dysfunction.
The primary function of REEP1 Gene Knockout Cell Lines is to model the loss of REEP1 function, allowing scientists to delve into the downstream effects of this genetic alteration on neuronal health and behavior. The absence of REEP1 facilitates the examination of altered protein interactions, disrupted cellular processes, and potential neurotoxic effects within cells. This system empowers researchers to generate insights into disease mechanisms, paving the way for finding novel therapeutic targets.
The scientific importance of REEP1 Gene Knockout Cell Lines is highlighted by their applications in both basic and translational research settings. They provide an invaluable platform for drug screening assays, targeted gene therapy studies, and the exploration of compensatory mechanisms that may arise in the wake of REEP1 loss. Unlike alternative cell lines, these knockout models offer a precise approach to studying specific gene functions in a controlled environment.
When compared to existing alternatives, REEP1 Gene Knockout Cell Lines stand out due to their high specificity and reproducibility in generating results that are directly attributable to the absence of REEP1. This reduces the complications arising from off-target effects and enhances the reliability of experimental outcomes, making them an essential resource for researchers aiming to elucidate genetic contributions to neurological disorders.
In conclusion, the unique characteristics and robust functionality of REEP1 Gene Knockout Cell Lines render them invaluable for clinical and research-focused organizations dedicated to the advancement of understanding and treating genetic diseases. With a portfolio designed to support cutting-edge research and a commitment to scientific excellence, our company is poised to deliver innovative solutions that empower scientists in their quest for knowledge and advancements in biological science.
Please note that all services are for research use only. Not intended for any clinical use.
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