Gene: RCOR1
Official Full Name: REST corepressor 1provided by HGNC
Gene Summary: This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29734 | RCOR1 Knockout cell line (HeLa) | Human | RCOR1 | 1:3~1:6 | Negative | Online Inquiry |
KO29735 | RCOR1 Knockout cell line (HCT 116) | Human | RCOR1 | 1:2~1:4 | Negative | Online Inquiry |
KO29736 | RCOR1 Knockout cell line (HEK293) | Human | RCOR1 | 1:3~1:6 | Negative | Online Inquiry |
RCOR1 Gene Knockout Cell Lines are advanced cellular models specifically engineered for the study of the RCOR1 gene, which encodes a critical component of the repressor complex involved in transcriptional regulation. By employing CRISPR-Cas9 technology, these cell lines effectively disrupt the RCOR1 gene, leading to the complete loss of its protein product. This knockout facilitates a deeper understanding of its role in various biological processes, including cell differentiation, development, and tumorigenesis.
The key function of these knockout cell lines is to serve as a platform for examining the functional consequences of RCOR1 absence on cellular behavior and signaling pathways. Researchers can utilize these models to study downstream effects, such as changes in gene expression profiles, alterations in cell cycle progression, and apoptosis-related mechanisms. Additionally, the RCOR1 knockout cell lines are particularly valuable in cancer research, where the modulation of transcriptional repression is often implicated in tumor development and progression.
The scientific importance of RCOR1 Gene Knockout Cell Lines extends to both basic research and clinical applications. In the context of therapeutic development, these models provide essential insights into potential drug targets and the molecular underpinnings of diseases linked to dysregulated transcriptional control. Furthermore, they are instrumental in the validation of gene therapy approaches, allowing for the exploration of compensatory mechanisms in the absence of key regulatory elements.
What sets our RCOR1 Gene Knockout Cell Lines apart from alternatives is the specificity and efficiency of gene editing achieved through our proprietary methods, combined with a thorough validation process ensuring reliable performance in experimental applications. This results in a consistently high-quality product that meets the rigorous demands of contemporary scientific investigation.
For researchers and clinicians focused on gene regulation, cancer biology, and therapeutic innovation, the RCOR1 Gene Knockout Cell Lines represent a crucial tool, enabling a more comprehensive approach to understanding complex biological systems. Our company, with years of expertise in producing high-precision biological products, is committed to supporting your research endeavors with this unparalleled tool tailored to advance scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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