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RASL11A Knockout Cell Lines

Gene: RASL11A

Official Full Name: RAS like family 11 member Aprovided by HGNC

Gene Summary: Predicted to enable G protein activity and GTP binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase I. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14700 RASL11A Knockout cell line (HCT 116) Human RASL11A 1:2~1:4 Negative Online Inquiry
KO14701 RASL11A Knockout cell line (HEK293) Human RASL11A 1:3~1:6 Negative Online Inquiry
KO14702 RASL11A Knockout cell line (A549) Human RASL11A 1:3~1:4 Negative Online Inquiry

Background

RASL11A Gene Knockout Cell Lines are genetically modified cell lines in which the RASL11A gene has been systematically disrupted, providing a unique tool for investigating the role of this gene in cellular processes. RASL11A is known to be involved in various signaling pathways, including those related to cell growth, differentiation, and oncogenesis. By creating knockout models, researchers can study the functional implications of RASL11A loss, revealing its contributions to tumor biology and potential as a therapeutic target.

The primary mechanism underlying these cell lines involves the precise use of CRISPR-Cas9 technology to induce frame-shifting mutations or deletions within the RASL11A gene. This targeted approach allows researchers to observe phenotypic changes in cellular behavior, such as proliferation rates, apoptosis, and response to drug treatments, ultimately elucidating the gene's functional role in pathophysiology. The ability to manipulate gene expression provides crucial insights for both basic biology and translational research, making these knockout lines invaluable for studying cancer mechanisms and therapeutic responses.

In scientific contexts, RASL11A Gene Knockout Cell Lines are particularly important for their applications in drug discovery and development. They facilitate high-throughput screening of compounds aimed at modulating RASL11A-associated pathways, thus streamlining the identification of novel therapeutic agents. Moreover, compared to traditional knockout methods, our cell lines offer enhanced specificity and efficiency, minimizing off-target effects that can confound experimental outcomes.

These cell lines’ unique selling points include their robust validation by leading researchers, comprehensive characterization, and the reliability of the knockout component, which ensures reproducibility across experiments. For researchers and clinicians aiming for rigor in their experimental designs, the utility of RASL11A Gene Knockout Cell Lines cannot be overstated, as they simplify complex genetic manipulation, enabling clear insights into gene function and interaction.

Our company is committed to advancing the frontiers of genetic research, blending cutting-edge technology with extensive expertise in cell line development to provide exceptional biological products that empower the scientific community. By choosing RASL11A Gene Knockout Cell Lines, you are investing in a resource that will enhance your research and translational efforts.

Please note that all services are for research use only. Not intended for any clinical use.

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