Home / RAPH1 Knockout Cell Lines

RAPH1 Knockout Cell Lines

Gene: RAPH1

Official Full Name: Ras association (RalGDS/AF-6) and pleckstrin homology domains 1provided by HGNC

Gene Summary: This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14705 RAPH1 Knockout cell line (HeLa) Human RAPH1 1:3~1:6 Negative Online Inquiry
KO14706 RAPH1 Knockout cell line (HCT 116) Human RAPH1 1:2~1:4 Negative Online Inquiry
KO14707 RAPH1 Knockout cell line (HEK293) Human RAPH1 1:3~1:6 Negative Online Inquiry
KO14708 RAPH1 Knockout cell line (A549) Human RAPH1 1:3~1:4 Negative Online Inquiry

Background

RAPH1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the RAPH1 gene, a critical component implicated in various cellular processes, including intracellular signaling and cytoskeletal dynamics. These knockout cell lines serve as essential tools for researchers aiming to elucidate the biological roles of RAPH1 and its potential contributions to disease pathology.

The primary function of RAPH1 revolves around its involvement in the regulation of actin dynamics and cell migration, essential processes in tissue homeostasis and repair. By utilizing these knockout cell lines, scientists can investigate the specific cellular mechanisms that are disrupted in the absence of RAPH1, allowing for a deeper understanding of its role in physiological and pathological contexts. The RAPH1 knockout model can be applied in various research disciplines including cancer biology, neurobiology, and developmental biology, facilitating studies on tumor progression, neuronal development, and immune responses.

The scientific importance of this product lies in its ability to provide a clear phenotype that researchers can analyze, yielding insights that might be obscured in wild-type cell lines. Compared to standard cell lines, which carry the RAPH1 gene, these knockout lines eliminate confounding variables, enabling precise investigations into RAPH1 signaling pathways and their implications in diseases. They are particularly advantageous for targeted therapeutics, as understanding gene function can inform drug design and improve treatment efficacy.

For researchers and clinicians, the value of RAPH1 Gene Knockout Cell Lines is immense; they offer a reliable and reproducible model for functional studies and drug screening, while facilitating the discovery of novel therapeutic targets. Our company specializes in providing high-quality biological products, and our expertise in cellular engineering ensures that you receive rigorously validated knockout lines that meet the highest scientific standards, thereby enhancing the robustness and reliability of your research outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.