Gene: RAD54L2
Official Full Name: RAD54 like 2provided by HGNC
Gene Summary: Predicted to enable ATP-dependent chromatin remodeler activity; protein kinase binding activity; and transcription coregulator activity. Predicted to be involved in chromatin organization. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nuclear speck. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29818 | RAD54L2 Knockout cell line (HeLa) | Human | RAD54L2 | 1:3~1:6 | Negative | Online Inquiry |
KO29819 | RAD54L2 Knockout cell line (HCT 116) | Human | RAD54L2 | 1:2~1:4 | Negative | Online Inquiry |
KO29820 | RAD54L2 Knockout cell line (HEK293) | Human | RAD54L2 | 1:3~1:6 | Negative | Online Inquiry |
KO29821 | RAD54L2 Knockout cell line (A549) | Human | RAD54L2 | 1:3~1:4 | Negative | Online Inquiry |
RAD54L2 Gene Knockout Cell Lines are specifically engineered cell lines in which the RAD54L2 gene, known for its role in DNA repair and homologous recombination, has been systematically disrupted. This product serves as a vital tool for researchers studying the intricate mechanisms of DNA damage repair, cellular responses to genotoxic stress, and the underlying pathways that contribute to genomic stability. By creating a cellular environment lacking RAD54L2, scientists can investigate how the absence of this protein influences various cellular processes, including cell cycle regulation, apoptosis, and chromosomal integrity.
The key function of these knockout cell lines lies in their ability to provide insights into the RAD54L2 gene's role during DNA repair processes. RAD54L2 is part of the ATP-dependent chromatin remodeling factors and is crucial for the successful repair of DNA double-strand breaks. Utilizing these cell lines allows researchers to dissect the pathways associated with RAD54L2 in a controlled setting, enabling the evaluation of compensatory mechanisms that other cellular factors may employ when this gene is non-functional.
Scientifically, the importance of RAD54L2 Gene Knockout Cell Lines spans multiple applications, including cancer research, where understanding DNA damage response mechanisms can lead to innovative therapeutic strategies. Furthermore, these models are invaluable for pharmacological studies as they facilitate screening for compounds that target DNA repair pathways, which may enhance the efficacy of existing anticancer therapies.
In comparison to other existing models, RAD54L2 knockout cell lines offer unique advantages through their specificity and reliability in mimicking the true genetic deficiency of RAD54L2. Additionally, they can be readily utilized alongside other cell lines and experimental setups, making them a versatile choice for complex experimental designs.
The value that RAD54L2 Gene Knockout Cell Lines provide to researchers and clinicians lies not only in their capability to illuminate the functional landscape of the RAD54L2 gene but also in their significance in advancing the understanding of cancer biology and therapeutic responses. By using these cell lines, scientists can pave the way for groundbreaking discoveries that could ultimately influence clinical practices.
Our company has extensive experience and expertise in developing high-quality biological products for fundamental and clinical research. We are dedicated to supporting the scientific community with innovative tools that advance the frontiers of knowledge in molecular biology and genetics.
Please note that all services are for research use only. Not intended for any clinical use.
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