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RAB40A Knockout Cell Lines

Gene: RAB40A

Official Full Name: RAB40A, member RAS oncogene familyprovided by HGNC

Gene Summary: This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. [provided by RefSeq, Apr 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24782 RAB40A Knockout cell line (HeLa) Human RAB40A 1:3~1:6 Negative Online Inquiry
KO24783 RAB40A Knockout cell line (HCT 116) Human RAB40A 1:2~1:4 Negative Online Inquiry
KO24784 RAB40A Knockout cell line (HEK293) Human RAB40A 1:3~1:6 Negative Online Inquiry

Background

RAB40A Gene Knockout Cell Lines are specialized cellular models designed to facilitate the investigation of gene function and the molecular mechanisms underlying various biological processes. These cell lines are engineered to have the RAB40A gene, a member of the RAB family of small GTPases involved in intracellular transport and signaling, selectively disrupted. By utilizing CRISPR/Cas9 technology for precise gene editing, researchers gain a powerful tool to study the functional consequences of RAB40A deficiency, which is implicated in diverse cellular activities, including endocytosis and protein degradation.

The primary mechanism of action involves the loss of functional RAB40A protein, leading to alterations in cellular pathways that rely on proper vesicle trafficking. This disruption can be instrumental in elucidating the roles of RAB40A in pathological conditions such as cancer, neurodegenerative diseases, and metabolic disorders. Furthermore, these knockout cell lines offer researchers a platform for testing therapeutic interventions that target RAB40A-related pathways, providing insights into potential clinical applications.

One of the significant advantages of RAB40A Gene Knockout Cell Lines is their ability to produce reproducible, consistent results in experimental settings, allowing for enhanced reliability in data interpretation. Compared to conventional methods that may involve transient knockdown approaches, these stable knockout models provide a more comprehensive and enduring understanding of RAB40A function.

For researchers and clinicians engaged in molecular biology and translational research, access to RAB40A Gene Knockout Cell Lines represents a valuable asset in their investigative toolbox. With these lines, users can accelerate their research into gene function and therapeutic development, ultimately leading to advancements in treatment options.

Our company is dedicated to delivering high-quality biological products and tools, fostering innovation and discovery in life sciences. With extensive expertise in gene editing technologies, we strive to support researchers in their quest to unravel complex biological phenomena and improve human health outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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