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RAB3C Knockout Cell Lines

Gene: RAB3C

Official Full Name: RAB3C, member RAS oncogene familyprovided by HGNC

Gene Summary: This gene is a member of the RAS oncogene family and encodes a small GTPase. Other similar small GTPases are known to be involved in vesicle trafficking, and the encoded protein was shown to play a role in recycling phagocytosed MHC class 1 complexes to the cell surface. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30577 RAB3C Knockout cell line (HeLa) Human RAB3C 1:3~1:6 Negative Online Inquiry

Background

RAB3C Gene Knockout Cell Lines are specially engineered cellular models that have had the RAB3C gene disrupted, enabling researchers to study the functional implications of this gene in a controlled environment. RAB3C is a member of the RAB protein family, which are small GTPases involved in the regulation of vesicle trafficking and secretion. By creating knockout versions of cell lines, these products allow scientists to investigate the direct role of RAB3C in various physiological and pathological processes, such as synaptic transmission, neurosecretion, and the development of certain diseases.

The fundamental mechanism at play involves the complete removal or disruption of the RAB3C gene, resulting in a loss of function that can be quantitatively assessed in vivo. This enables a wide range of experimental assays to investigate the downstream effects of RAB3C repression, including alterations in neurotransmitter release, changes in cell signaling pathways, and impacts on cellular morphology. Scientific studies utilizing RAB3C knockout cell lines can lead to valuable insights into neurodegeneration and other disorders.

The scientific importance of these knockout cell lines is underscored by their applications in both basic research and clinical settings. They are pivotal in drug discovery efforts by serving as reliable models to test the efficacy of therapeutic candidates targeting neuronal trafficking mechanisms. By comparing RAB3C knockout cells with wild-type counterparts, researchers can elucidate the genetic and molecular pathways involved in various diseases, aiding in the development of targeted therapies.

Unique selling points of the RAB3C Gene Knockout Cell Lines include their high specificity, which minimizes off-target effects, and their compatibility with a variety of functional assays such as fluorescence microscopy and electrophysiological studies. This makes them a versatile tool for diverse experimental applications. Furthermore, the reliability and reproducibility inherent in these cell lines offer a level of consistency that is often lacking in alternative models.

For researchers and clinicians, these knockout cell lines represent a practical entry point into a deeper understanding of the complex roles that RAB3C plays in cellular dynamics. Enhancing the ability to investigate the interplay of genes and their products in cellular processes is invaluable for the development of therapies aimed at neurological conditions, metabolic disorders, and beyond.

Our company is dedicated to providing high-quality biological products and solutions, leveraging rigorous scientific expertise and cutting-edge technology to support the research community in exploring complex biological questions. By choosing RAB3C Gene Knockout Cell Lines, you are investing in a powerful research tool designed to advance scientific inquiry and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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