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QTRT2 Knockout Cell Lines

Gene: QTRT2

Official Full Name: queuine tRNA-ribosyltransferase accessory subunit 2provided by HGNC

Gene Summary: This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02583 QTRT2 Knockout cell line (HeLa) Human QTRT2 1:3~1:6 Negative Online Inquiry
KO02584 QTRT2 Knockout cell line (HCT 116) Human QTRT2 1:2~1:4 Negative Online Inquiry
KO02585 QTRT2 Knockout cell line (HEK293) Human QTRT2 1:3~1:6 Negative Online Inquiry
KO02586 QTRT2 Knockout cell line (A549) Human QTRT2 1:3~1:4 Negative Online Inquiry

Background

QTRT2 Gene Knockout Cell Lines are specialized biological tools engineered for the precise elimination of the QTRT2 gene in various cell types, enabling comprehensive investigation into gene function and related pathways. Utilizing CRISPR-Cas9 technology, these cell lines offer researchers the capability to create targeted gene disruptions efficiently, facilitating the study of gene expression, cellular responses, and protein interactions.

The primary function of QTRT2 Gene Knockout Cell Lines revolves around their ability to mimic loss-of-function mutations associated with the QTRT2 gene. By eliminating this gene, researchers can observe phenotypic changes and alterations in cellular processes, providing insights into its biological role, particularly in cellular metabolism and disease models. These cell lines serve as vital resources in elucidating mechanisms underlying disorders linked to QTRT2 dysfunction, thereby contributing to the growing understanding of genetic bases of diseases.

In both research and clinical settings, the QTRT2 Gene Knockout Cell Lines represent a crucial advancement in genomics and molecular biology. Their applications extend to drug discovery, functional genomics, and therapeutic research, offering a platform for screening potential pharmacological agents that target pathways influenced by the QTRT2 gene.

Distinct advantages of QTRT2 Gene Knockout Cell Lines include their high specificity, reproducibility, and ease of use compared to traditional knockout methods, such as homologous recombination. Moreover, their readiness for immediate application in diverse experimental contexts allows for accelerated research timelines.

For researchers and clinicians focused on genetic pathways and their implications in diseases, the QTRT2 Gene Knockout Cell Lines provide an invaluable asset that enhances the exploration of targeted therapies and innovative treatment strategies. Our company prides itself on delivering high-quality biological products and has extensive expertise in cell line development, ensuring that our offerings, including the QTRT2 Gene Knockout Cell Lines, meet the precise needs of scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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