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PURG Knockout Cell Lines

Gene: PURG

Official Full Name: purine rich element binding protein Gprovided by HGNC

Gene Summary: The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. [provided by RefSeq, Apr 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26920 PURG Knockout cell line (HEK293) Human PURG 1:3~1:6 Negative Online Inquiry

Background

PURG Gene Knockout Cell Lines are a revolutionary suite of genetically engineered cell lines designed to facilitate precise manipulation of gene function for research and therapeutic applications. These cell lines utilize CRISPR-Cas9 technology to effectively create knockout models, significantly enhancing the study of gene function, disease mechanisms, and the efficacy of therapeutic interventions.

The primary mechanism of action involves the targeted disruption of specific genes through the introduction of double-strand breaks, subsequently repaired via error-prone pathways that result in gene knockout. This allows researchers to observe the phenotypic consequences of gene inactivation, elucidate gene interactions, and explore compensatory pathways. The PURG Gene Knockout Cell Lines are particularly valuable for studying complex biological processes, such as cell signaling, metabolism, and genetic diseases, offering insights that are crucial for advancing both basic and applied biomedical research.

In clinical settings, these cell lines can be instrumental in drug discovery, enabling high-throughput screening of compounds that may restore normal function in diseases caused by gene mutations. Their robust and reproducible nature allows for consistent results, making them ideal for longitudinal studies and therapeutic development.

What sets PURG Gene Knockout Cell Lines apart from other conventional knockout systems is the precision and efficiency of the gene editing, coupled with a comprehensive supporting database that provides essential information on each cell line’s genetic background. This reduces the time researchers typically spend on validation and characterization, thus accelerating the pace of scientific discovery.

For researchers and clinicians, the value of PURG Gene Knockout Cell Lines lies in their ability to streamline experimental workflows, enhance reproducibility, and provide a deeper understanding of the genetic basis of diseases. By choosing PURG, users gain access to a premium product backed by extensive expertise in genetic engineering and a commitment to innovation in life sciences.

As a leading provider of cutting-edge biological products, our company is dedicated to advancing research through high-quality tools such as the PURG Gene Knockout Cell Lines, empowering scientists to make transformative discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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