Gene: PRDX2
Official Full Name: peroxiredoxin 2provided by HGNC
Gene Summary: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20732 | PRDX2 Knockout cell line (HeLa) | Human | PRDX2 | 1:3~1:6 | Negative | Online Inquiry |
KO20733 | PRDX2 Knockout cell line (HCT 116) | Human | PRDX2 | 1:2~1:4 | Negative | Online Inquiry |
KO20734 | PRDX2 Knockout cell line (HEK293) | Human | PRDX2 | 1:3~1:6 | Negative | Online Inquiry |
KO20735 | PRDX2 Knockout cell line (A549) | Human | PRDX2 | 1:3~1:4 | Negative | Online Inquiry |
PRDX2 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the functional consequences of the loss of the Peroxiredoxin 2 (PRDX2) gene. PRDX2 plays an essential role in regulating oxidative stress within cells by catalyzing the reduction of peroxides, thereby protecting cellular components from oxidative damage. By knocking out this gene, researchers can elucidate the pathways impacted by increased oxidative stress, revealing insights into various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
The key functions of PRDX2 Gene Knockout Cell Lines lie in the exploration of redox biology and its influence on cellular responses to stressors. These cell lines allow scientists to manipulate and observe changes in cell proliferation, apoptosis, and reactive oxygen species (ROS) accumulation. Through functional assays and molecular characterization, researchers can examine how PRDX2 absence affects cellular signaling pathways and gene expression, contributing to our understanding of disease mechanisms.
The scientific importance of these cell lines is far-reaching; they serve as a crucial tool for drug discovery and therapeutic interventions aimed at diseases where oxidative stress plays a critical role. In clinical settings, findings from studies utilizing PRDX2 knockout models can inform strategies for managing conditions linked to oxidative damage, opening avenues for targeted therapies.
A distinctive advantage of PRDX2 Gene Knockout Cell Lines compared to alternative models is their specific targeting of the PRDX2 gene, which ensures a clear and controlled environment to study its unique contributions to cellular function. Unlike general oxidative stress models, these cell lines provide a focused approach that allows researchers to obtain precise data on the role of PRDX2 in various biological processes.
For researchers, clinicians, and drug developers, the availability of PRDX2 Gene Knockout Cell Lines significantly enhances experimental rigor and reliability, offering a profound understanding of oxidative stress pathways. Our company's expertise in genetic engineering and commitment to providing validated and high-performance biological products underpins our ability to support cutting-edge research that drives innovation in health and disease management.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.