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PPP6R3 Knockout Cell Lines

Gene: PPP6R3

Official Full Name: protein phosphatase 6 regulatory subunit 3provided by HGNC

Gene Summary: Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14916 PPP6R3 Knockout cell line (HeLa) Human PPP6R3 1:3~1:6 Negative Online Inquiry
KO14917 PPP6R3 Knockout cell line (HCT 116) Human PPP6R3 1:2~1:4 Negative Online Inquiry
KO14918 PPP6R3 Knockout cell line (HEK293) Human PPP6R3 1:3~1:6 Negative Online Inquiry
KO14919 PPP6R3 Knockout cell line (A549) Human PPP6R3 1:3~1:4 Negative Online Inquiry

Background

PPP6R3 Gene Knockout Cell Lines are advanced cellular models designed for in-depth studies of the PPP6R3 gene, a crucial regulator within the protein phosphatase 6 complex implicated in various cellular processes such as cell cycle regulation, apoptosis, and stress response. These knockout cell lines have been meticulously engineered to eliminate the expression of the PPP6R3 gene, thus providing researchers with the opportunity to elucidate its function by observing the resulting phenotypic changes and biochemical pathways.

The key function of these cell lines revolves around their ability to serve as a powerful tool for dissecting the molecular mechanisms that govern signaling pathways. By generating a complete knockout of the PPP6R3 protein, researchers can investigate how its absence affects cellular behaviors, including proliferation, migration, and response to therapeutic agents. This mechanism of action enables a clearer understanding of the role that PPP6R3 plays in both normal physiology and disease states, particularly in cancer research and developmental biology.

The scientific significance of PPP6R3 Gene Knockout Cell Lines is profound, particularly in research scenarios aiming to uncover novel therapeutic targets or biomarkers. These cell lines are applicable in a wide range of research fields, including oncology and neurology, where understanding the intricate regulatory networks is essential for developing innovative treatment strategies.

In comparison to alternative cell models, our PPP6R3 Gene Knockout Cell Lines offer unparalleled specificity and precision. Unlike conventional knockdown approaches that often leave residual gene expression, our knockout technology ensures a complete and stable gene loss, enhancing the reliability of experimental outcomes. Furthermore, these cell lines are validated for consistent performance, allowing researchers to reproduce results with greater confidence.

For researchers, clinicians, and biotechnology developers, the value of PPP6R3 Gene Knockout Cell Lines lies not only in their role as a research tool but also as a means to accelerate the pace of scientific discovery. By incorporating these sophisticated models into their workflows, users can gain deeper insights into the effects of PPP6R3 modulation, paving the way for breakthroughs in understanding disease mechanisms and advancing therapeutic interventions.

Our company prides itself on providing high-quality biological products backed by a robust foundation of scientific expertise and innovation. We are committed to facilitating groundbreaking research and advancing the life sciences through top-tier offerings like our PPP6R3 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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