Gene: PPP1R32
Official Full Name: stabilizer of axonemal microtubules 4provided by HGNC
Gene Summary: Enables phosphatase binding activity. Predicted to be involved in flagellated sperm motility. Located in ciliary basal body. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28167 | PPP1R32 Knockout cell line (HCT 116) | Human | PPP1R32 | 1:2~1:4 | Negative | Online Inquiry |
KO28168 | PPP1R32 Knockout cell line (HEK293) | Human | PPP1R32 | 1:3~1:6 | Negative | Online Inquiry |
PPP1R32 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the PPP1R32 gene, which encodes the protein phosphatase 1 regulatory subunit 32. This gene plays a critical role in the regulation of various signaling pathways and cellular processes by modulating the activity of protein phosphatases. By providing researchers with a platform to study the functional consequences of PPP1R32 deficiency, these knockout cell lines facilitate a deeper understanding of its role in cellular homeostasis, signal transduction, and potential implications in diseases.
The key functions of the PPP1R32 Gene Knockout Cell Lines center on dissecting the molecular pathways affected by the absence of this regulatory subunit. Researchers can observe alterations in phosphorylation states of target proteins and assess downstream signaling impacts, yielding insights into cellular functions such as proliferation, apoptosis, and differentiation. These models are particularly useful in elucidating the involvement of PPP1R32 in various pathological conditions, including cancer and neurodegenerative diseases, enabling the identification of potential therapeutic targets.
The scientific importance of these cell lines extends beyond basic research; they possess practical applications in drug development and disease modeling. By offering a reliable means to study gene function and interaction networks within a controlled environment, they represent a vital tool for clinicians and researchers aiming to discover novel interventions and enhance understanding of disease mechanisms.
One of the distinct advantages of the PPP1R32 Gene Knockout Cell Lines is their specificity and ease of use compared to alternative models, such as transient knockdown systems or other gene-editing techniques like CRISPR. The knockout approach provides a stable and reproducible system, allowing for long-term studies and reliable comparisons across experiments.
For researchers, clinicians, and pharmaceutical developers, these cell lines serve as invaluable assets in the quest for innovative therapies and a more profound comprehension of cell biology. Their robust design and the ability to help delineate complex biological questions underscore their significance in both academic and clinical research.
Our company is devoted to advancing scientific discovery by offering high-quality biological products, evidenced by our expertise in producing reliable and innovative cellular models. The PPP1R32 Gene Knockout Cell Lines exemplify our commitment to supporting the research community with cutting-edge tools that enhance the understanding of genetic determinants in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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