Gene: PPP1R1A
Official Full Name: protein phosphatase 1 regulatory inhibitor subunit 1Aprovided by HGNC
Gene Summary: Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35952 | PPP1R1A Knockout cell line (HCT 116) | Human | PPP1R1A | 1:2~1:4 | Negative | Online Inquiry |
KO35953 | PPP1R1A Knockout cell line (HEK293) | Human | PPP1R1A | 1:3~1:6 | Negative | Online Inquiry |
PPP1R1A Gene Knockout Cell Lines are specialized biological tools designed to facilitate the in-depth study of the role played by the protein phosphatase 1 regulatory subunit 1A (PPP1R1A) in various cellular processes. These engineered cell lines have undergone precise genetic modifications to completely disrupt the expression of the PPP1R1A gene, allowing researchers to observe the effects of this alteration on cellular signaling pathways and disease mechanisms.
The primary function of these knockout cell lines is to elucidate the biological functions of PPP1R1A, which is known to regulate protein phosphatase 1 (PP1) activity, impacting a multitude of processes including cell division, metabolism, and development. By removing the expression of PPP1R1A, researchers can investigate its downstream effects on modulating phosphorylation states and its subsequent influence on protein activity and cellular behavior.
The scientific importance of PPP1R1A Gene Knockout Cell Lines lies in their application across various research fields, including cancer biology, neurobiology, and metabolic disorders. In clinical research, these models assist in drug development assays, enabling the identification of potential therapeutic targets through the observation of phenotypic changes in the absence of PPP1R1A.
Unique selling points of our PPP1R1A Gene Knockout Cell Lines include their high specificity and consistent performance, which are achieved through advanced CRISPR-Cas9 technology that ensures precise genome editing. Compared to other alternatives, these cell lines are validated for reproducibility across experiments, providing researchers with reliable data that enhances the credibility of their findings.
Researchers and clinicians will find significant value in these knockout cell lines as they not only aid in hypothesis testing but also offer insights that could lead to breakthroughs in understanding disease mechanisms and identifying therapeutic interventions. With our company's extensive experience in developing innovative biological products, we ensure that our PPP1R1A Gene Knockout Cell Lines are delivered with rigorous quality control, supporting researchers in their quest to advance scientific knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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