Gene: PPP1R18
Official Full Name: protein phosphatase 1 regulatory subunit 18provided by HGNC
Gene Summary: Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14934 | PPP1R18 Knockout cell line (HeLa) | Human | PPP1R18 | 1:3~1:6 | Negative | Online Inquiry |
KO14935 | PPP1R18 Knockout cell line (HCT 116) | Human | PPP1R18 | 1:2~1:4 | Negative | Online Inquiry |
KO14936 | PPP1R18 Knockout cell line (HEK293) | Human | PPP1R18 | 1:3~1:6 | Negative | Online Inquiry |
KO14937 | PPP1R18 Knockout cell line (A549) | Human | PPP1R18 | 1:3~1:4 | Negative | Online Inquiry |
PPP1R18 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology research, facilitating the in-depth study of the PPP1R18 gene's functions and its associated pathways. These engineered cell lines are specifically designed to have a targeted deletion of the PPP1R18 gene, effectively eliminating its expression. This knockout allows researchers to elucidate the gene's role in various biological processes, from cellular signaling to developmental biology.
The primary function of PPP1R18 is to code for a regulatory protein that interacts with protein phosphatase 1 (PP1), essential for many cellular activities including metabolic regulation, cell division, and apoptosis. By utilizing these knockout cell lines, researchers gain insights into the signaling cascades where PPP1R18 is implicated, revealing critical findings related to its contribution to diseases such as cancer and metabolic disorders.
The scientific importance of these cell lines cannot be overstated. They serve as an invaluable resource in both academic and clinical settings for elucidating gene function, investigating disease mechanisms, and elucidating potential therapeutic targets. Their applications extend to drug discovery, where understanding the gene's pathways may identify novel intervention strategies.
What sets our PPP1R18 Gene Knockout Cell Lines apart from conventional models is their precise genetic modification, which ensures consistent results across experiments. Unlike other models that can exhibit compensatory effects or incomplete knockout, these cell lines offer researchers the confidence of a clean genetic background, enhancing the robustness of experimental outcomes.
The value of PPP1R18 Gene Knockout Cell Lines lies in their ability to provide a clearer understanding of gene function, which is crucial for advancing therapeutic strategies. Whether you are a researcher delving into fundamental biology or a clinician exploring personalized medicine approaches, these cell lines facilitate a direct examination of gene function and disease pathology.
Our company brings a wealth of expertise in genetic engineering and molecular biology, ensuring that our products not only meet the highest standards of quality but also empower researchers with the tools necessary to drive scientific innovation forward.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.