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PPFIA4 Knockout Cell Lines

Gene: PPFIA4

Official Full Name: PTPRF interacting protein alpha 4provided by HGNC

Gene Summary: PPFIA4, or liprin-alpha-4, belongs to the liprin-alpha gene family. See liprin-alpha-1 (LIP1, or PPFIA1; MIM 611054) for background on liprins.[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34126 PPFIA4 Knockout cell line (HCT 116) Human PPFIA4 1:2~1:4 Negative Online Inquiry
KO34127 PPFIA4 Knockout cell line (HEK293) Human PPFIA4 1:3~1:6 Negative Online Inquiry

Background

PPFIA4 Gene Knockout Cell Lines are a specialized tool engineered to facilitate the study of the PPFIA4 gene, which is an important regulator of synaptic function and signaling pathways. These cell lines, created through advanced gene-editing techniques such as CRISPR-Cas9, are designed to eliminate the expression of the PPFIA4 gene, allowing researchers to investigate the resultant phenotypic changes and molecular mechanisms that occur in its absence.

The primary function of the PPFIA4 knockout is to serve as a model for understanding the role of PPFIA4 in cellular processes, including neuronal development, synapse formation, and plasticity. By elucidating the pathways influenced by PPFIA4, researchers can gain insights into various neurobiological disorders, including schizophrenia and autism spectrum disorders, where PPFIA4 may be implicated. The knockout cell lines can be utilized for high-throughput screening, drug testing, and functional assays, making them invaluable for both basic and applied research.

The scientific importance of PPFIA4 Knockout Cell Lines extends to translational research, where findings from these models can inform the development of targeted therapies. Compared to conventional wild-type cell lines, these knockout models provide a distinctly clearer view of gene function, enabling more accurate interpretations of experimental data and resulting in higher confidence in subsequent findings.

A significant advantage of our PPFIA4 Gene Knockout Cell Lines is their ease of use and reliability. They come fully validated and characterized, saving researchers from time-consuming initial optimization and allowing them to focus on their primary research objectives. Furthermore, our extensive technical support ensures that users can efficiently incorporate these cell lines into their research workflows.

By utilizing PPFIA4 Gene Knockout Cell Lines, researchers and clinicians can unlock new avenues in the study of molecular mechanisms underpinning neurodevelopmental disorders. As a leader in cutting-edge biological products, our company is committed to supporting the scientific community with high-quality, innovative research tools that advance the understanding of complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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