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PODXL2 Knockout Cell Lines

Gene: PODXL2

Official Full Name: podocalyxin like 2provided by HGNC

Gene Summary: This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins. [provided by RefSeq, Oct 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23406 PODXL2 Knockout cell line (HeLa) Human PODXL2 1:3~1:6 Negative Online Inquiry
KO23407 PODXL2 Knockout cell line (HCT 116) Human PODXL2 1:2~1:4 Negative Online Inquiry
KO23408 PODXL2 Knockout cell line (HEK293) Human PODXL2 1:3~1:6 Negative Online Inquiry
KO23409 PODXL2 Knockout cell line (A549) Human PODXL2 1:3~1:4 Negative Online Inquiry

Background

PODXL2 Gene Knockout Cell Lines represent a groundbreaking advancement in the field of cellular and molecular biology, providing researchers with an invaluable tool for investigating the role of the PODXL2 gene in various physiological and pathological processes. These cell lines are engineered to have a targeted deletion of the PODXL2 gene, enabling scientists to study the gene's function in cell behavior, signaling pathways, and disease mechanisms.

The key mechanism of action for these knockout cell lines revolves around the disruption of the Podocalyxin-like 2 (PODXL2) gene, which has been implicated in cell adhesion, proliferation, and migration. By utilizing these cell lines, researchers can evaluate how the absence of PODXL2 affects cellular processes such as tumor formation, immune response, and tissue regeneration. The ability to manipulate gene expression at this level allows for precise experimental setups, opening avenues for elucidating the gene's contributions to diseases like cancer, cardiovascular disorders, and autoimmune conditions.

The scientific importance of PODXL2 Gene Knockout Cell Lines is evident in their diverse applications in both basic and applied research settings. They empower researchers to explore novel therapeutic targets, validate drug efficacy, and examine gene-environment interactions, thereby driving forward the fields of genetic research and translational medicine.

Compared to conventional cell lines that may express PODXL2, these knockout lines offer distinct advantages. Researchers benefit from a clear control over gene expression, allowing for more accurate interpretation of experimental results. Additionally, their availability in multiple cellular backgrounds enhances the versatility of experimental designs, catering to various research needs.

For researchers and clinicians alike, PODXL2 Gene Knockout Cell Lines deliver unmatched value by facilitating in-depth study of gene function and helping to bridge the gap between laboratory findings and clinical applications. These cell lines represent a high-quality resource that could expedite the development of targeted therapies and biomarker identification.

Our company is dedicated to advancing scientific research through the development and provision of innovative biological tools, and PODXL2 Gene Knockout Cell Lines exemplify our commitment to supporting the scientific community in unraveling complex biological questions.

Please note that all services are for research use only. Not intended for any clinical use.

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