Gene: PNCK
Official Full Name: pregnancy up-regulated nonubiquitous CaM kinaseprovided by HGNC
Gene Summary: PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25844 | PNCK Knockout cell line (HEK293) | Human | PNCK | 1:3~1:6 | Negative | Online Inquiry |
PNCK Gene Knockout Cell Lines are genetically engineered cellular models specifically designed for investigating the biological role of the PNCK (Pseudouridine Synthase 1) gene. These cell lines have undergone precise gene editing techniques, such as CRISPR/Cas9, to knock out the PNCK gene, enabling researchers to study the consequences of its absence on cellular processes, signaling pathways, and overall cellular behavior.
The primary function of PNCK Gene Knockout Cell Lines is to facilitate a deeper understanding of the PNCK gene's contributions to cellular metabolism and proliferation. By eliminating this gene, scientists can analyze compensatory mechanisms that other pathways might invoke, thereby elucidating its role in physiological and pathological contexts. The knockout model is essential for investigating the involvement of PNCK in diseases, especially metabolic disorders and cancer, where altered cell signaling can lead to aberrant growth and survival.
In both research and clinical settings, PNCK Gene Knockout Cell Lines are invaluable tools for drug discovery and therapeutics targeting pathways influenced by PNCK. They provide a cellular framework for testing the efficacy of potential pharmaceutical compounds and unraveling the molecular mechanisms underlying disease conditions. Researchers can also utilize these models to identify biomarkers for therapeutic intervention and gain insights into patient stratification based on PNCK expression profiles.
One of the significant advantages of PNCK Gene Knockout Cell Lines is their specificity and the reproducibility of results, which are crucial for obtaining robust experimental data. Compared to traditional knockdown approaches, knockout models offer more comprehensive insights into gene function, as they eliminate the gene entirely, allowing researchers to observe the long-term effects without residual gene activity.
Ultimately, the inherent value of PNCK Gene Knockout Cell Lines lies in their ability to provide a clearer understanding of gene function in health and disease. They serve as essential resources for advancing biomedical research, making them a highly sought-after product for researchers and clinicians alike. Our company specializes in the development of advanced genetic tools, underpinning our commitment to providing high-quality biological products that empower the scientific community to achieve groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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