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PLXND1 Knockout Cell Lines

Gene: PLXND1

Official Full Name: plexin D1provided by HGNC

Gene Summary: Enables protein domain specific binding activity. Predicted to be involved in several processes, including positive regulation of axonogenesis; semaphorin-plexin signaling pathway; and synapse assembly. Predicted to act upstream of or within circulatory system development; dichotomous subdivision of terminal units involved in salivary gland branching; and kidney development. Located in lamellipodium. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29826 PLXND1 Knockout cell line (HeLa) Human PLXND1 1:3~1:6 Negative Online Inquiry
KO29827 PLXND1 Knockout cell line (HCT 116) Human PLXND1 1:2~1:4 Negative Online Inquiry
KO29828 PLXND1 Knockout cell line (HEK293) Human PLXND1 1:3~1:6 Negative Online Inquiry
KO29829 PLXND1 Knockout cell line (A549) Human PLXND1 1:3~1:4 Negative Online Inquiry

Background

PLXND1 Gene Knockout Cell Lines are specialized cellular models designed to investigate the functional role of the PLXND1 gene in various biological processes. These cell lines are generated through advanced gene editing techniques, specifically utilizing CRISPR/Cas9 technology. By knocking out the PLXND1 gene, researchers can study its involvement in cellular signaling pathways, immune responses, and developmental processes, which are essential for understanding diseases such as cancer, cardiovascular conditions, and immune disorders.

The key mechanism underlying the PLXND1 knockout cell lines is the precise alteration of the genome, resulting in the complete disruption of PLXND1 expression. This disruption allows scientists to assess changes in cellular behavior, including proliferation, migration, and apoptosis. As PLXND1 is known to play a pivotal role in processes such as cell-to-cell interactions and the regulation of angiogenesis, these knockout cell lines serve as an invaluable tool for dissecting the molecular mechanisms at play in health and disease.

The scientific importance of PLXND1 Gene Knockout Cell Lines extends to both basic and translational research. They provide insights into the biology of various cell types, informing drug development, therapeutic strategies, and potential biomarkers for disease progression. In clinical settings, understanding the role of PLXND1 could lead to novel interventions in areas where traditional therapies have been inadequate.

What sets our PLXND1 Gene Knockout Cell Lines apart from alternatives is their superior specificity and efficiency in gene editing, paired with a commitment to quality control in their production. The reliability of these models ensures that researchers can expect consistent and reproducible results within their experimental workflows. Furthermore, our cell lines are available with comprehensive support documentation and user protocols, facilitating their integration into diverse research applications.

In summary, investing in PLXND1 Gene Knockout Cell Lines empowers researchers and clinicians with the necessary tools to uncover critical biological insights, driving forward advancements in health and medicine. Our company prides itself on providing high-quality biotechnological products backed by extensive expertise in the field, ensuring our customers receive the best resources for their research pursuits.

Please note that all services are for research use only. Not intended for any clinical use.

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