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PLCD4 Knockout Cell Lines

Gene: PLCD4

Official Full Name: phospholipase C delta 4provided by HGNC

Gene Summary: This gene encodes a member of the delta class of phospholipase C enzymes. Phospholipase C enzymes play a critical role in many cellular processes by hydrolyzing phosphatidylinositol 4,5-bisphosphate into two intracellular second messengers, inositol 1,4,5-trisphosphate and diacylglycerol. Expression of this gene may be a marker for cancer. [provided by RefSeq, Jan 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08033 PLCD4 Knockout cell line (HeLa) Human PLCD4 1:3~1:6 Negative Online Inquiry
KO08034 PLCD4 Knockout cell line (A549) Human PLCD4 1:3~1:4 Negative Online Inquiry

Background

PLCD4 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to eliminate the functionality of the phospholipase C delta 4 (PLCD4) gene. These knockout cell lines serve as powerful tools in biological research, particularly in the study of signaling pathways, cellular proliferation, differentiation, and various disease mechanisms, including cancer and neurodegenerative disorders. By removing the PLCD4 gene, researchers can investigate the precise role of this protein in cellular function and its impact on intracellular calcium signaling and lipid metabolism.

The key mechanism of these PLCD4 knockout cell lines centers around the disruption of phosphoinositide signaling pathways. The absence of PLCD4 leads to alterations in downstream signaling cascades that are pivotal for cell growth and survival. This unique feature allows researchers to elucidate the physiological and pathological roles of PLCD4 in different biological contexts. Applications of PLCD4 knockout cell lines extend to translational medicine, where understanding the consequences of PLCD4 disruption can inform potential therapeutic strategies for PLCD4-related diseases.

One of the significant advantages of using PLCD4 Gene Knockout Cell Lines is the specificity it offers in studying gene function without the confounding effects of other cellular mechanisms. Standard cell lines with functioning PLCD4 may not convey the same insights into the gene's role, making the knockout models essential for targeted research. These cell lines provide a clear and controllable experimental model, enhancing reproducibility and reliability.

For researchers and clinicians alike, PLCD4 Gene Knockout Cell Lines represent a vital resource for advancing the understanding of cellular dynamics and disease processes. By using these knockout models, studies can lead to sharper insights that may pave the way for innovative therapeutic interventions. Our company prides itself on delivering high-quality genetic models, and our expertise in producing specialized cell lines ensures that you have the best tools available for your cutting-edge research efforts.

Please note that all services are for research use only. Not intended for any clinical use.

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